PDF(Pubmed)
Abstract：
Approximately 39 million people worldwide live with human immunodeficiency virus (HIV), and antiretroviral therapy (ART) has improved life expectancy for these individuals, with quality of life (QoL) being a crucial aspect. However, there is limited information on oral health-related quality of life (OHRQoL) for institutionalized patients with HIV. This study used a cross-sectional design and included 43 residents of a non-governmental institution who had a confirmed HIV diagnosis and a history of intravenous drug use. The Spanish version of the Oral Health Index Profile-14 (OHIPsp) was used to assess the OHRQoL, with the 50th percentile serving as the cutoff for good or poor quality of life. All 43 patients had one or more oral lesions, with 44.1% having AIDS-related oral lesions (AROLs). Over half of the participants (48.8%) reported a poor OHRQoL, and females experienced worse quality of life in all dimensions compared to males. Subjects with AROLs were three times more likely to have poor OHRQoL than those without AROLs (p = 0.03; OR = 3.1 IC 1.04-9.6). These results highlight the need for a comprehensive treatment plan for patients with HIV that includes oral health, particularly for women living in precarious conditions or who are institutionalized. Improving oral health can significantly enhance quality of life.
摘要：
全球约有3900万人感染人类免疫缺陷病毒（HIV）。抗逆转录病毒疗法（ART）改善了这些人的预期寿命，生活质量(QoL)是一个至关重要的方面。然而,关于住院HIV患者口腔健康相关生活质量(OHRQoL)的信息有限.这项研究采用了横断面设计，包括43名非政府机构的居民，他们被确诊为HIV并有静脉吸毒史。西班牙语版的口腔健康指数概况-14（OHIPsp）用于评估OHRQoL，将第50百分位数作为生活质量好或差的界限。所有43例患者都有一个或多个口腔病变，44.1%患有艾滋病相关口腔病变(AROLs)。超过一半的参与者（48.8%）报告OHRQoL较差，与男性相比，女性在所有方面的生活质量都较差。患有AROL的受试者的OHRQoL较差的可能性是没有AROL的受试者的三倍（p=0.03；OR=3.1IC1.04-9.6）。这些结果凸显了对HIV患者的全面治疗计划的必要性，包括口腔健康，特别是对于生活在不稳定条件下或被制度化的妇女。改善口腔健康可以显著提高生活质量。
