PDF(Pubmed)
Abstract：
Carbon-based nanomaterials, such as carbon quantum dots (CQDs) and carbon 2D nanosheets (graphene, graphene oxide, and graphdiyne), have shown remarkable potential in various biological applications. CQDs offer tunable photoluminescence and excellent biocompatibility, making them suitable for bioimaging, drug delivery, biosensing, and photodynamic therapy. Additionally, CQDs\' unique properties enable bioimaging-guided therapy and targeted imaging of biomolecules. On the other hand, carbon 2D nanosheets exhibit exceptional physicochemical attributes, with graphene excelling in biosensing and bioimaging, also in drug delivery and antimicrobial applications, and graphdiyne in tissue engineering. Their properties, such as tunable porosity and high surface area, contribute to controlled drug release and enhanced tissue regeneration. However, challenges, including long-term biocompatibility and large-scale synthesis, necessitate further research. Potential future directions encompass theranostics, immunomodulation, neural interfaces, bioelectronic medicine, and expanding bioimaging capabilities. In summary, both CQDs and carbon 2D nanosheets hold promise to revolutionize biomedical sciences, offering innovative solutions and improved therapies in diverse biological contexts. Addressing current challenges will unlock their full potential and can shape the future of medicine and biotechnology.
摘要：
碳基纳米材料,如碳量子点(CQDs)和碳二维纳米片(石墨烯，氧化石墨烯,和石墨烯)，在各种生物应用中显示出巨大的潜力。CQDs提供可调的光致发光和优异的生物相容性，使它们适合生物成像，药物输送,生物传感，和光动力疗法。此外,CQDs的独特特性使生物成像指导治疗和生物分子的靶向成像成为可能。另一方面,碳二维纳米片表现出优异的物理化学属性，石墨烯在生物传感和生物成像方面表现出色，在药物输送和抗菌应用中，和石墨炔在组织工程中的应用。他们的财产,如可调孔隙率和高表面积，有助于控制药物释放和增强组织再生。然而,挑战,包括长期生物相容性和大规模合成，需要进一步的研究。潜在的未来方向包括治疗学，免疫调节,神经接口，生物电子医学，和扩大生物成像能力。总之,CQD和碳2D纳米片都有望彻底改变生物医学科学，在不同的生物环境中提供创新的解决方案和改进的疗法。应对当前的挑战将释放其全部潜力，并可以塑造医学和生物技术的未来。
