PDF(Pubmed)
Abstract：
The aim of this study was to assess the relationship between the daily consumption of 50 g of chocolate with 85% cocoa content and the severity of acne lesions.
METHODS: The study involved 92 participants with acne who were divided into two groups, A (n = 51) and B (n = 41). In the first week, both groups had to follow an anti-inflammatory diet (AID), then for the next 4 weeks, group A continued on with the AID, and group B followed an AID with chocolate. After this time, group B started a 4-week AID without chocolate, and group A started a 4-week AID with chocolate. The severity of acne lesions was assessed using the Investigator\'s Static Global Assessment scale, where zero points indicated no lesions and five points indicated severe acne.
RESULTS: As a result of the consumption of 50 g of chocolate, a statistically significant intensification of acne lesions was observed in both groups. After 4 weeks of following the chocolate diet, the severity of acne lesions increased from 2.5 ± 0.7 to 3.4 ± 0.8 points (p < 0.0001) in group A, and from 2.4 ± 0.7 to 3.5 ± 0.6 points (p < 0.0001) in group B. Overall, chocolate intake contributed to the exacerbation of acne lesions by one point in 65 participants, by two points in 13 participants and by three points in one participant.
CONCLUSIONS: The obtained results suggest that daily consumption of 50 g of chocolate with 85% cocoa content, even with an anti-inflammatory diet, may intensify acne lesions in this study group. However, it remains unclear which chocolate components may lead to the exacerbation of acne.
METHODS: The study involved 92 participants with acne who were divided into two groups, A (n = 51) and B (n = 41). In the first week, both groups had to follow an anti-inflammatory diet (AID), then for the next 4 weeks, group A continued on with the AID, and group B followed an AID with chocolate. After this time, group B started a 4-week AID without chocolate, and group A started a 4-week AID with chocolate. The severity of acne lesions was assessed using the Investigator\'s Static Global Assessment scale, where zero points indicated no lesions and five points indicated severe acne.
RESULTS: As a result of the consumption of 50 g of chocolate, a statistically significant intensification of acne lesions was observed in both groups. After 4 weeks of following the chocolate diet, the severity of acne lesions increased from 2.5 ± 0.7 to 3.4 ± 0.8 points (p < 0.0001) in group A, and from 2.4 ± 0.7 to 3.5 ± 0.6 points (p < 0.0001) in group B. Overall, chocolate intake contributed to the exacerbation of acne lesions by one point in 65 participants, by two points in 13 participants and by three points in one participant.
CONCLUSIONS: The obtained results suggest that daily consumption of 50 g of chocolate with 85% cocoa content, even with an anti-inflammatory diet, may intensify acne lesions in this study group. However, it remains unclear which chocolate components may lead to the exacerbation of acne.
摘要：
这项研究的目的是评估每天食用50克可可含量为85％的巧克力与痤疮病变严重程度之间的关系。
方法：该研究涉及92名痤疮患者，分为两组，A(n=51)和B(n=41)。在第一周,两组都必须遵循抗炎饮食（AID），接下来的4周,A组继续AID,B组接受了巧克力辅助治疗。在这段时间之后,B组开始为期4周的无巧克力援助，A组开始了为期4周的巧克力援助。使用研究者的静态全球评估量表评估痤疮病变的严重程度，其中零点表示无病变，五点表示严重痤疮。
结果：由于消耗了50克巧克力，两组均观察到有统计学意义的痤疮病变加剧.在遵循巧克力饮食4周后，A组痤疮病变的严重程度从2.5±0.7增加到3.4±0.8分（p<0.0001），B组从2.4±0.7到3.5±0.6分(p<0.0001)。巧克力摄入量导致65名参与者痤疮病变加重1分，13名参与者中的2分，一名参与者中的3分。
结论：获得的结果表明，每天食用50克可可含量为85％的巧克力，即使有抗炎的饮食，可能会加剧本研究组的痤疮病变。然而,目前尚不清楚哪些巧克力成分可能导致痤疮恶化。
方法：该研究涉及92名痤疮患者，分为两组，A(n=51)和B(n=41)。在第一周,两组都必须遵循抗炎饮食（AID），接下来的4周,A组继续AID,B组接受了巧克力辅助治疗。在这段时间之后,B组开始为期4周的无巧克力援助，A组开始了为期4周的巧克力援助。使用研究者的静态全球评估量表评估痤疮病变的严重程度，其中零点表示无病变，五点表示严重痤疮。
结果：由于消耗了50克巧克力，两组均观察到有统计学意义的痤疮病变加剧.在遵循巧克力饮食4周后，A组痤疮病变的严重程度从2.5±0.7增加到3.4±0.8分（p<0.0001），B组从2.4±0.7到3.5±0.6分(p<0.0001)。巧克力摄入量导致65名参与者痤疮病变加重1分，13名参与者中的2分，一名参与者中的3分。
结论：获得的结果表明，每天食用50克可可含量为85％的巧克力，即使有抗炎的饮食，可能会加剧本研究组的痤疮病变。然而,目前尚不清楚哪些巧克力成分可能导致痤疮恶化。
