PDF(Pubmed)
Abstract：
Pulmonary hypertension (PH) is a consequence of pulmonary endarteritis during infection with Dirofilaria immitis in dogs. Echocardiography is the technique of choice but is not always accessible to all clinicians. This study aimed to evaluate the association of the radiological findings in dogs with heartworm disease and the presence or absence of echocardiographically characterised PH. The study included 62 heartworm-infected dogs that underwent thoracic radiographs and echocardiography. The studied dogs showed moderate to severe PH when the Right Pulmonary Artery Distensibility (RPAD) Index was <29.5%. The RPAD Index was used for comparison with thoracic radiographs. The Vertebral Heart Size (VHS), right cranial pulmonary artery passing through the fourth rib in the laterolateral projection (CrPA/R4) ratio, and right caudal pulmonary artery to the ninth rib in the dorsoventral projection (CdPA/R9) ratio showed significant differences between dogs with/without PH (p < 0.001). Sensitivity (sen) and specificity (sp) cut-off values were obtained: VHS ≥ 9.53 (sen 93.75%, sp 63.33%); CrPA/R4 ≥ 1.08 (sen 87.5%, sp 70%); and CdPA/R9 ≥ 1.10 (sen 96.88%, sp 76.66%). The CrPA/R4 and CdPA/R9 ratios showed potential as a preliminary screening tool for PH in heartworm-infected dogs, suggesting that they may reliably indicate the presence of PH and guide the decision for further diagnostic testing.
摘要：
肺动脉高压（PH）是狗感染Dirofilariaimmitis期间肺动脉内膜炎的结果。超声心动图是首选技术，但并非所有临床医生都能使用。这项研究旨在评估患有心丝虫病的狗的放射学发现与超声心动图表征的PH的存在与否之间的关联。该研究包括62只感染心丝虫的狗，这些狗接受了胸片和超声心动图检查。当右肺动脉扩张性（RPAD）指数<29.5％时，研究的狗显示中度至重度PH。RPAD指数用于与胸片比较。椎体心脏大小（VHS）右颅肺动脉通过第四肋外侧投影（CrPA/R4）的比值，右尾肺动脉至第九肋背腹侧投影（CdPA/R9）比值在有/无PH犬之间显示出显着差异（p<0.001）。获得敏感性（sen）和特异性（sp）临界值：VHS≥9.53（sen93.75％，sp63.33%)；CrPA/R4≥1.08(森87.5%，sp70%)；CdPA/R9≥1.10(森96.88%，sp76.66%）。CrPA/R4和CdPA/R9的比率显示出潜在的初步筛查工具，用于感染心丝虫的狗的PH。表明它们可以可靠地指示PH的存在，并指导进一步诊断测试的决定。
