PDF(Pubmed)
Abstract：
Oxidative stress may affect new born calves due to high stress suffered around birth. We hypothesized that maternal supplementation with micronutrients and vitamins in late gestation enhance the neonatal calf\'s antioxidant system, decreasing the occurrence and duration of diarrhea, and improving growth from birth through weaning. To test this hypothesis, 80 multiparous cows were cluster-assigned to treatment groups. Treated group (TG) cows received mineral and vitamin supplementation while control group (CG) cows received saline solution. Feed intake and fecal score were measured daily until the ninth week. Weight and body measurements were registered weekly, and blood samples were collected from postpartum cows and calves after birth and at 7, 14, and 63 days of life. Although CG calves had greater fecal scores (p = 0.01), diarrhea characteristics did not differ. Calves in the TG showed greater starter intake (p = 0.04). Feed efficiency showed a trend with treatment-age interaction (p = 0.06). Calves in the CG had wider hips in the first week (p = 0.03), but not by the ninth week. Total antioxidant status, thiobarbituric acid reactive substances, and haptoglobin did not differ between treatment groups. Serum metabolites showed no differences. Supplementation did not impact calf antioxidant system or growth in the first two months.
摘要：
由于出生前后的高压力，氧化应激可能会影响新生的小牛。我们假设孕妇在妊娠后期补充微量营养素和维生素可增强新生儿小牛的抗氧化系统，减少腹泻的发生和持续时间，从出生到断奶促进生长。为了检验这个假设，将80头多胎母牛集群分配到治疗组。处理组(TG)母牛接受矿物质和维生素补充,而对照组(CG)母牛接受盐溶液。每天测量饲料摄入量和粪便评分，直到第九周。每周进行体重和身体测量，在出生后以及生命的7、14和63天，从产后母牛和小牛中收集血液样本。尽管CG小牛的粪便评分更高（p=0.01），腹泻的特点没有差异。TG中的小牛显示出更大的起始摄入量（p=0.04）。饲料效率与处理年龄的相互作用呈趋势（p=0.06）。CG中的小牛在第一周臀部较宽（p=0.03），但不是第九周。总抗氧化剂状态，硫代巴比妥酸反应性物质，和触珠蛋白在治疗组之间没有差异。血清代谢产物无差异。在前两个月，补充不会影响小腿抗氧化系统或生长。
