PDF(Pubmed)
Abstract：
BACKGROUND: The aim of Part II of this two-part study is to describe and analyze the association of various aspects and measurements related to the morphometry of the skull and craniocervical region to CM/SM status of Pomeranians, by means of computed tomography (CT) and magnetic resonance imaging (MRI).
METHODS: Prospectively, Pomeranians were included that underwent both CT and MRI studies of the head and cervicothoracic vertebral column. For those cases where qualitative classifications differed between observers, the experienced observer re-evaluated the studies and decided on a final classification that was used for further analysis. For quantitative measurements, the means of the observers\' measurements were used for analysis.
RESULTS: Among statistically significant differences in measurements, we found that dogs with SM had a significantly shorter clivus length based on both MRI (p = 0.01) and CT measurements (p = 0.01), and a significantly smaller caudal cranial fossa area based on both MRI (p = 0.02) and CT measurements (p = 0.02).
CONCLUSIONS: Significant morphometrical differences were identified between dogs with or without CM/SM. The findings in this study add to those already described in other breeds and provide further insight into factors that may play a role in the pathogenesis of CM/SM in Pomeranians.
METHODS: Prospectively, Pomeranians were included that underwent both CT and MRI studies of the head and cervicothoracic vertebral column. For those cases where qualitative classifications differed between observers, the experienced observer re-evaluated the studies and decided on a final classification that was used for further analysis. For quantitative measurements, the means of the observers\' measurements were used for analysis.
RESULTS: Among statistically significant differences in measurements, we found that dogs with SM had a significantly shorter clivus length based on both MRI (p = 0.01) and CT measurements (p = 0.01), and a significantly smaller caudal cranial fossa area based on both MRI (p = 0.02) and CT measurements (p = 0.02).
CONCLUSIONS: Significant morphometrical differences were identified between dogs with or without CM/SM. The findings in this study add to those already described in other breeds and provide further insight into factors that may play a role in the pathogenesis of CM/SM in Pomeranians.
摘要：
背景：这项由两部分组成的研究的第二部分的目的是描述和分析与颅骨和颅颈区域的形态计量学有关的各个方面和测量与波美拉尼亚的CM/SM状态的关联，通过计算机断层扫描（CT）和磁共振成像（MRI）。
方法：前瞻性，包括Pomeranians，他们对头部和颈胸脊柱进行了CT和MRI研究。对于观察者之间定性分类不同的情况，有经验的观察者重新评估了研究,并决定了用于进一步分析的最终分类.对于定量测量，观察者的测量值用于分析。
结果：在测量结果的统计学显着差异中，根据MRI（p=0.01）和CT测量（p=0.01），我们发现SM犬的斜坡长度明显较短，根据MRI（p=0.02）和CT测量（p=0.02），尾颅窝面积明显较小。
结论：在有或没有CM/SM的狗之间发现了显着的形态统计学差异。这项研究的发现增加了其他品种中已经描述的发现，并提供了对可能在波美拉尼亚CM/SM发病机理中起作用的因素的进一步见解。
方法：前瞻性，包括Pomeranians，他们对头部和颈胸脊柱进行了CT和MRI研究。对于观察者之间定性分类不同的情况，有经验的观察者重新评估了研究,并决定了用于进一步分析的最终分类.对于定量测量，观察者的测量值用于分析。
结果：在测量结果的统计学显着差异中，根据MRI（p=0.01）和CT测量（p=0.01），我们发现SM犬的斜坡长度明显较短，根据MRI（p=0.02）和CT测量（p=0.02），尾颅窝面积明显较小。
结论：在有或没有CM/SM的狗之间发现了显着的形态统计学差异。这项研究的发现增加了其他品种中已经描述的发现，并提供了对可能在波美拉尼亚CM/SM发病机理中起作用的因素的进一步见解。
