关键词: Coupling reagents Fmoc solid-phase synthesis Linkers Resins

Mesh : Solid-Phase Synthesis Techniques / methods Peptides / chemical synthesis chemistry Fluorenes / chemistry Amino Acids / chemistry

来  源:   DOI:10.1007/978-1-0716-3914-6_3

Abstract:
Synthetic peptides are important as drugs and in research. Currently, the method of choice for producing these compounds is solid-phase peptide synthesis. Here, we describe the scope and limitations of Fmoc solid-phase peptide synthesis. Furthermore, we provide a detailed protocol for Fmoc peptide synthesis.
摘要:
合成肽作为药物和研究中很重要。目前,制备这些化合物的选择方法是固相肽合成。这里,我们描述了Fmoc固相肽合成的范围和局限性。此外,我们提供了Fmoc肽合成的详细方案。
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