Abstract：
Aside from human bones, epoxy-based synthetic bones are regarded as the gold standard for biomechanical testing os osteosyntheses. There is a significant discrepancy in biomechanical testing between the determination of fracture stability due to implant treatment in experimental methods and their ability to predict the outcome of stability and fracture healing in a patient. One possible explanation for this disparity is the absence of population-specific variables such as age, gender, and ethnicity in artificial bone, which may influence the geometry and mechanical properties of bone. The goal of this review was to determine whether commercially available artificial bones adequately represent human anatomical variability for mechanical testing of femoral osteosyntheses. To summarize, the availability of suitable bone surrogates currently limits the validity of mechanical evaluations of implant-bone constructs. The currently available synthetic bones neither accurately reflect the local mechanical properties of human bone, nor adequately represent the necessary variability between various populations, limiting their generalized clinical relevance.
摘要：
除了人类的骨头,环氧基合成骨被认为是骨合成生物力学测试的金标准。在生物力学测试中，由于实验方法中的植入物治疗而确定的骨折稳定性与其预测患者稳定性和骨折愈合结果的能力之间存在显着差异。这种差异的一个可能的解释是缺乏特定于人口的变量，如年龄，性别,和人造骨的种族，这可能会影响骨骼的几何形状和机械性能。这篇综述的目的是确定市售人造骨是否足以代表股骨骨合成的机械测试的人体解剖学变异性。总结一下,目前,合适的骨替代物的可用性限制了种植体-骨结构的机械评估的有效性.目前可用的合成骨都不能准确反映人体骨的局部力学性能,也不能充分代表不同人群之间的必要差异，限制了它们的普遍临床相关性。
