Abstract：
OBJECTIVE: This study aimed to assess the effect of silver diamine fluoride (SDF) combined with photodynamic therapy (PDT) on primary enamel microhardness.
METHODS: This in vitro, experimental study was conducted on 40 extracted primary molars with sound buccal/lingual surfaces. The baseline enamel microhardness of the teeth was initially measured by a Vickers hardness tester. Next, the teeth were randomly assigned to four groups (n=10) for treatment with SDF, PDT, SDF plus PDT, and control (no intervention). After the intervention, the teeth underwent a 14-day pH-cycling, and enamel microhardness was measured again. The change in microhardness was calculated for each group, and comparisons were made by two-way ANOVA and t-test (alpha=0.05).
RESULTS: The mean secondary microhardness of the three intervention groups was significantly higher than that of the control group (P<0.05). Despite slightly higher microhardness in SDF + PDT group, followed by the SDF group, the difference in secondary microhardness was not significant among the three intervention groups (P>0.05).
CONCLUSIONS: Treatment of primary enamel with SDF or PDT can increase its microhardness and enhance remineralization. However, combined use of SDF and PDT had no additional advantage over the use of SDF alone.
METHODS: This in vitro, experimental study was conducted on 40 extracted primary molars with sound buccal/lingual surfaces. The baseline enamel microhardness of the teeth was initially measured by a Vickers hardness tester. Next, the teeth were randomly assigned to four groups (n=10) for treatment with SDF, PDT, SDF plus PDT, and control (no intervention). After the intervention, the teeth underwent a 14-day pH-cycling, and enamel microhardness was measured again. The change in microhardness was calculated for each group, and comparisons were made by two-way ANOVA and t-test (alpha=0.05).
RESULTS: The mean secondary microhardness of the three intervention groups was significantly higher than that of the control group (P<0.05). Despite slightly higher microhardness in SDF + PDT group, followed by the SDF group, the difference in secondary microhardness was not significant among the three intervention groups (P>0.05).
CONCLUSIONS: Treatment of primary enamel with SDF or PDT can increase its microhardness and enhance remineralization. However, combined use of SDF and PDT had no additional advantage over the use of SDF alone.
摘要：
目的：本研究旨在评估二氟化银（SDF）联合光动力疗法（PDT）对初级釉质显微硬度的影响。
方法：这在体外，对40颗提取的颊/舌面健全的初级磨牙进行了实验研究。最初通过维氏硬度测试仪测量牙齿的基线釉质显微硬度。接下来,牙齿被随机分为四组（n=10）进行SDF治疗，PDT,SDF加PDT,和控制（无干预）。干预之后,牙齿经历了14天的pH值循环，再次测量牙釉质显微硬度。计算每组的显微硬度变化，并通过双向方差分析和t检验(α=0.05)进行比较。
结果：三个干预组的平均次要显微硬度明显高于对照组（P<0.05）。尽管SDF+PDT组的显微硬度略高，其次是自卫队，3个干预组的次生显微硬度差异无统计学意义(P>0.05)。
结论：用SDF或PDT治疗原发性牙釉质可增加其显微硬度并增强再矿化。然而,联合使用SDF和PDT与单独使用SDF相比没有额外优势.
方法：这在体外，对40颗提取的颊/舌面健全的初级磨牙进行了实验研究。最初通过维氏硬度测试仪测量牙齿的基线釉质显微硬度。接下来,牙齿被随机分为四组（n=10）进行SDF治疗，PDT,SDF加PDT,和控制（无干预）。干预之后,牙齿经历了14天的pH值循环，再次测量牙釉质显微硬度。计算每组的显微硬度变化，并通过双向方差分析和t检验(α=0.05)进行比较。
结果：三个干预组的平均次要显微硬度明显高于对照组（P<0.05）。尽管SDF+PDT组的显微硬度略高，其次是自卫队，3个干预组的次生显微硬度差异无统计学意义(P>0.05)。
结论：用SDF或PDT治疗原发性牙釉质可增加其显微硬度并增强再矿化。然而,联合使用SDF和PDT与单独使用SDF相比没有额外优势.
