OBJECTIVE: To explore the application value of conventional MRI combined with DWI sequences in the diagnosis of microprolactinomas.
METHODS: Prospective.
METHODS: Thirty-four patients in microprolactinomas with high signal on T2WI (HT2-PRL) group (34 females, 34 ± 7 years), 26 patients in microprolactinomas with equal or low signal on T2WI (ELT2-PRL) group (21 females, 34 ± 7 years), 35 patients with hyperprolactinemia (33 females, 32 ± 8 years), and 30 normal controls (25 females, 31 ± 7 years).
UNASSIGNED: TSE sequence at 3 T.
RESULTS: Pituitary morphological parameters (such as length and volume), dynamic contrast-enhanced parameters (such as time to peak) and the apparent diffusion coefficients (ADCs) were measured in each group.
METHODS: ANOVA and Mann-Whitney U test were used to compare parameters among groups. Spearman\'s coefficient was used to evaluate the correlation between variables. ROC analysis was used to assess the performance of the parameters. A P-value <0.05 was considered statistically significant.
RESULTS: The pituitary volume of patients in HT2-PRL, ELT2-PRL, and hyperprolactinemia group were 831.00 (747.60, 887.60), 923.63 ± 219.34, and 737.20 (606.40, 836.80) mm3. The pituitary maximum height in these three groups were 7.03 (6.43, 8.63), 8.03 ± 1.41, and 6.63 ± 1.28 mm, respectively. The lesion ADC value was significantly correlated with T2 relative signal intensity (the ratio of signal intensity of microprolactinoma or anterior pituitary to left temporal cortex) (r = 0.821). Compared with patients with hyperprolactinemia, the diagnostic efficacy of T2 relative signal intensity was higher in HT2-PRL group, with an AUC of 0.954, whereas the ADC value was the highest in ELT2-PRL group, with an AUC of 0.924.
CONCLUSIONS: DWI sequences can be used to assist in the diagnosis of pituitary microadenomas.
METHODS: 1 TECHNICAL EFFICACY: Stage 2.
目的:探讨常规MRI结合DWI序列在微泌乳素腺瘤诊断中的应用价值。
方法:前瞻性。
方法:T2WI(HT2-PRL)组34例微泌乳素瘤高信号患者(34例女性,34±7年),T2WI(ELT2-PRL)组中信号相等或低的微泌乳素瘤患者26例(女性21例,34±7年),35例高泌乳素血症(33例女性,32±8年),和30名正常对照(25名女性,31±7年)。
■3T处的TSE序列
结果:垂体形态学参数(例如长度和体积),测量各组动态对比增强参数(如达峰时间)和表观扩散系数(ADC).
方法:采用方差分析和Mann-WhitneyU检验比较各组参数。采用Spearman系数评价变量之间的相关性。ROC分析用于评估参数的性能。P值<0.05被认为具有统计学意义。
结果:HT2-PRL患者的垂体体积,ELT2-PRL,高泌乳素血症组为831.00(747.60,887.60),923.63±219.34和737.20(606.40,836.80)mm3。三组的最大垂体高度分别为7.03(6.43,8.63),8.03±1.41,6.63±1.28mm,分别。病变ADC值与T2相对信号强度(微泌乳素瘤或垂体前叶与左颞叶皮质的信号强度之比)显着相关(r=0.821)。与高泌乳素血症患者相比,T2相对信号强度在HT2-PRL组中的诊断效能更高,AUC为0.954,而ELT2-PRL组的ADC值最高,AUC为0.924。
结论:DWI序列可用于垂体微腺瘤的辅助诊断。
方法:1技术效果:阶段2。