PDF(Pubmed)
Abstract：
Aerobic capacity, defined as peak oxygen uptake (peakVO2), is a marker for aerobic fitness and is associated with left ventricular (LV) systolic and diastolic function. The aim of the study was to explore the relation between left atrial (LA) volume index (LAVI) and aerobic capacity in healthy young male adults. One hundred three healthy young male subjects (mean age: 34.2 ± 5.5years) were consecutively included in the study. All subjects underwent echocardiography to assess LAVI, LV systolic and diastolic functions. Aerobic capacity was assessed by cardiopulmonary exercise testing. All patients had normal left ventricular ejection fraction (LVEF). One hundred one subjects had normal LAVI (≤34 mL/m2) while 2 subjects had mildly increased LAVI (35-41 mL/m2). Mean peakVO2 predicted was 82.2 ± 14.4%. 64subjects (62.1%) had a peakVO2 < 85% of age-predicted and sex-predicted values and they had higher LAVI compared to those who had a peakVO2 higher than 85% of age-predicted and sex-predicted values (22.0 ± 4.8 mL/m2 vs 20.3 ± 4.1 mL/m2, P = .055). Notably, only LAVI showed a significant correlation with peakVO2 and predicted breathing reserve (BR), while anaerobic threshold correlated with both LAVI and LVEF. Age was also a significant factor, negatively impacting peakVO2 (r = -0.265, P = .007) and predicted BR (r = -0.282, P = .004). Multivariate analysis revealed that both LAVI and age were independent predictors of peakVO2 and predicted BR. This study suggests that LAVI can be a valuable indicator of aerobic capacity in apparently healthy young males.
摘要：
有氧能力，定义为峰值摄氧量(peakVO2)，是有氧健身的标志，与左心室（LV）收缩和舒张功能有关。该研究的目的是探讨健康年轻男性成年人的左心房（LA）容积指数（LAVI）与有氧能力之间的关系。研究连续纳入了103名健康的年轻男性受试者（平均年龄：34.2±5.5岁）。所有受试者均接受超声心动图评估LAVI，左心室收缩和舒张功能。有氧能力通过心肺运动测试进行评估。所有患者左心室射血分数（LVEF）均正常。100名受试者的LAVI正常（≤34mL/m2），而2名受试者的LAVI轻度增加（35-41mL/m2）。预测的平均峰值VO2为82.2±14.4％。64名受试者（62.1％）的峰值VO2<年龄预测值和性别预测值的85％，与峰值VO2高于年龄预测值和性别预测值的85％的人相比，他们的LAVI更高（22.0±4.8mL/m2vs20.3±4.1mL/m2，P=.055）。值得注意的是,只有LAVI与峰值VO2和预测呼吸储备(BR)有显著相关性，而无氧阈值与LAVI和LVEF均相关。年龄也是一个重要因素，负面影响峰值VO2(r=-0.265，P=.007)和预测BR(r=-0.282，P=.004)。多因素分析显示，LAVI和年龄是峰值VO2和预测BR的独立预测因子。这项研究表明，LAVI可以成为明显健康的年轻男性有氧能力的有价值指标。
