Abstract：
Tetrahydrocannabivarin (THCV) is a phytocannabinoid that is becoming popular across the North American cannabis market. THCV has been reported to reduce blood sugar and act as an appetite suppressant in several independent pre-clinical studies, which has earned it the popular nickname of \"diet weed,\" despite few human studies of these effects. Additionally, THCV is usually and incorrectly categorized as an intoxicating analogue of tetrahydrocannabinol (THC), which causes confusion among both consumers and regulators. In this article, we examine what is known pre-clinically and clinically about THCV, as well as highlight mechanisms of action, in order to clarify the scientific differences between THCV and THC. THCV, although structurally similar to THC, has distinct pharmacological activity and physiological effects at the doses currently reported in the literature. We highlight areas of opportunity for further THCV research in order to determine the full and appropriate potential for unique health, wellness, and therapeutic applications of this compound.
摘要：
四氢大麻酚（THCV）是一种植物大麻素，在北美大麻市场上越来越受欢迎。据报道，在几项独立的临床前研究中，THCV可以降低血糖并作为食欲抑制剂。这为它赢得了“减肥杂草”的流行绰号，“尽管对这些影响的人类研究很少。此外,THCV通常被错误地归类为四氢大麻酚（THC）的令人陶醉的类似物，这在消费者和监管机构之间造成了混乱。在这篇文章中,我们检查了临床前和临床上关于THCV的已知情况，并强调行动机制，为了阐明THCV和THC之间的科学差异。THCV,虽然在结构上与THC相似，在文献中目前报道的剂量下具有不同的药理活性和生理作用。我们强调了进一步THCV研究的机会领域，以确定独特健康的全部和适当潜力，健康,和该化合物的治疗应用。
