Abstract：
UNASSIGNED: Quantitative muscle ultrasound (QMUS) is potentially valuable as a diagnostic tool in central neurological disorders, as it provides information about changes in muscle architecture. This study aimed to investigate whether ultrasound images of the submental and masticatory muscles in children with spastic cerebral palsy (CP) differ from those obtained in a reference group, and whether observed ultrasound abnormalities differ between subgroups of children with different Eating and Drinking Ability Classification System (EDACS) levels to support its construct validity.
UNASSIGNED: A prospective cohort study was conducted in 25 children with spastic CP aged 3-18 years. QMUS of selected muscles was performed. Muscle thickness and echogenicity in the CP group were compared to previously collected reference values, and between different EDACS levels within the CP group.
UNASSIGNED: Median echogenicity of all muscles was significantly higher in children with CP than in healthy controls. The temporalis muscle was significantly thinner in the CP group. There were no differences in muscle thickness or echogenicity between EDACS levels.
UNASSIGNED: QMUS is able to detect abnormal architecture of submental and masticatory muscles in children with spastic CP, but the interpretation of abnormalities in relation to the severity of mastication and swallowing problems needs further investigation.
UNASSIGNED: A prospective cohort study was conducted in 25 children with spastic CP aged 3-18 years. QMUS of selected muscles was performed. Muscle thickness and echogenicity in the CP group were compared to previously collected reference values, and between different EDACS levels within the CP group.
UNASSIGNED: Median echogenicity of all muscles was significantly higher in children with CP than in healthy controls. The temporalis muscle was significantly thinner in the CP group. There were no differences in muscle thickness or echogenicity between EDACS levels.
UNASSIGNED: QMUS is able to detect abnormal architecture of submental and masticatory muscles in children with spastic CP, but the interpretation of abnormalities in relation to the severity of mastication and swallowing problems needs further investigation.
摘要：
■定量肌肉超声（QMUS）作为中枢神经疾病的诊断工具具有潜在的价值，因为它提供了有关肌肉结构变化的信息。这项研究旨在调查痉挛型脑瘫（CP）儿童的下巴和咀嚼肌的超声图像是否与参考组中获得的图像不同。以及观察到的超声异常是否在饮食能力分类系统（EDACS）水平不同的儿童亚组之间存在差异，以支持其结构效度。
■在25名3-18岁的痉挛型CP患儿中进行了一项前瞻性队列研究。对选定的肌肉进行QMUS。将CP组的肌肉厚度和回声与先前收集的参考值进行比较，以及CP组内不同EDACS水平之间。
■CP患儿所有肌肉的回声中位数明显高于健康对照组。CP组颞肌明显变薄。EDACS水平之间的肌肉厚度或回声没有差异。
■QMUS能够检测出痉挛型CP患儿的下颌和咀嚼肌的异常结构，但是，与咀嚼和吞咽问题的严重程度有关的异常解释需要进一步研究。
■在25名3-18岁的痉挛型CP患儿中进行了一项前瞻性队列研究。对选定的肌肉进行QMUS。将CP组的肌肉厚度和回声与先前收集的参考值进行比较，以及CP组内不同EDACS水平之间。
■CP患儿所有肌肉的回声中位数明显高于健康对照组。CP组颞肌明显变薄。EDACS水平之间的肌肉厚度或回声没有差异。
■QMUS能够检测出痉挛型CP患儿的下颌和咀嚼肌的异常结构，但是，与咀嚼和吞咽问题的严重程度有关的异常解释需要进一步研究。
