Abstract：
OBJECTIVE: To investigate the impact of cerebellopontine angle (CPA) masses on subjective and measured taste function.
METHODS: Retrospective cross-sectional study.
METHODS: Tertiary referral center.
METHODS: Consecutive adult patients with untreated CPA masses.
METHODS: Gustatory function was psychophysically measured with Taste Strips (range, 0-16) on both sides of the tongue. Subjective taste complaints were assessed using a questionnaire.
METHODS: Half-sided taste impairment (hemi-ageusia) was defined as side-to-side asymmetry ≥4 points with <9 points on the side of the CPA mass. We used the Koos classification for vestibular schwannomas (VS) and, in the case of facial nerve palsy, the House-Brackmann grading system.
RESULTS: We included 135 patients (mean [standard deviation (SD)] age, 55.3 ± 14.1 yr; 62 males). The most common CPA mass was VS (77%). Overall, the measured taste function was lower on the affected compared with the healthy side of the tongue (mean score, 9.8 ± 3.3 versus 11 ± 2.9; p < 0.0001). Looking for clinically relevant one-sided taste impairment revealed 18 (13.3%) patients with hemi-ageusia, but only 4 (30.8%) of those subjectively complained of taste dysfunction. Regarding VS, Koos IV masses presented the lowest score on the affected side (mean score, 7.5 ± 3.7). Six patients presented with facial palsy. Having facial palsy did not result in a lower Taste Strips score (p = 0.23).
CONCLUSIONS: Before any CPA mass treatment, a measurable ipsilateral decrease in gustatory function is present in many patients. Most patients do not notice this preexisting taste impairment. From a medicolegal standpoint, this warrants consideration. To avoid postoperative claims regarding taste function, a preoperative assessment may be considered.
METHODS: Retrospective cross-sectional study.
METHODS: Tertiary referral center.
METHODS: Consecutive adult patients with untreated CPA masses.
METHODS: Gustatory function was psychophysically measured with Taste Strips (range, 0-16) on both sides of the tongue. Subjective taste complaints were assessed using a questionnaire.
METHODS: Half-sided taste impairment (hemi-ageusia) was defined as side-to-side asymmetry ≥4 points with <9 points on the side of the CPA mass. We used the Koos classification for vestibular schwannomas (VS) and, in the case of facial nerve palsy, the House-Brackmann grading system.
RESULTS: We included 135 patients (mean [standard deviation (SD)] age, 55.3 ± 14.1 yr; 62 males). The most common CPA mass was VS (77%). Overall, the measured taste function was lower on the affected compared with the healthy side of the tongue (mean score, 9.8 ± 3.3 versus 11 ± 2.9; p < 0.0001). Looking for clinically relevant one-sided taste impairment revealed 18 (13.3%) patients with hemi-ageusia, but only 4 (30.8%) of those subjectively complained of taste dysfunction. Regarding VS, Koos IV masses presented the lowest score on the affected side (mean score, 7.5 ± 3.7). Six patients presented with facial palsy. Having facial palsy did not result in a lower Taste Strips score (p = 0.23).
CONCLUSIONS: Before any CPA mass treatment, a measurable ipsilateral decrease in gustatory function is present in many patients. Most patients do not notice this preexisting taste impairment. From a medicolegal standpoint, this warrants consideration. To avoid postoperative claims regarding taste function, a preoperative assessment may be considered.
摘要：
目的：研究桥小脑角（CPA）质量对主观和测量味觉功能的影响。
方法：回顾性横断面研究。
方法：三级转诊中心。
方法：连续成年患者未治疗的CPA肿块。
方法：味觉功能是用味觉条（范围，0-16）在舌头的两侧。使用问卷评估主观口味投诉。
方法：半侧味觉障碍（半侧味觉障碍）定义为侧侧不对称≥4点，CPA质量侧<9点。我们使用Koos分类来治疗前庭神经鞘瘤(VS)，在面神经麻痹的情况下，House-Brackmann分级制度.
结果：我们包括135名患者（平均[标准差（SD）]年龄，55.3±14.1岁；62名男性）。最常见的CPA质量是VS(77%)。总的来说,与舌头的健康侧相比，受影响的患者测得的味觉功能较低(平均评分，9.8±3.3对11±2.9；p<0.0001)。寻找临床相关的单侧味觉障碍，发现18例（13.3％）患有半味觉障碍的患者，但只有4人(30.8%)主观抱怨味觉功能障碍。关于VS,KoosIV肿块在患侧得分最低(平均得分，7.5±3.7)。6例患者出现面部麻痹。面部麻痹不会导致较低的味觉评分（p=0.23）。
结论：在任何CPA大规模治疗之前，许多患者存在可测量的同侧味觉功能下降。大多数患者没有注意到这种预先存在的味觉障碍。从法医学的角度来看，这值得考虑。为了避免术后对味觉功能的要求，术前评估可以考虑.
方法：回顾性横断面研究。
方法：三级转诊中心。
方法：连续成年患者未治疗的CPA肿块。
方法：味觉功能是用味觉条（范围，0-16）在舌头的两侧。使用问卷评估主观口味投诉。
方法：半侧味觉障碍（半侧味觉障碍）定义为侧侧不对称≥4点，CPA质量侧<9点。我们使用Koos分类来治疗前庭神经鞘瘤(VS)，在面神经麻痹的情况下，House-Brackmann分级制度.
结果：我们包括135名患者（平均[标准差（SD）]年龄，55.3±14.1岁；62名男性）。最常见的CPA质量是VS(77%)。总的来说,与舌头的健康侧相比，受影响的患者测得的味觉功能较低(平均评分，9.8±3.3对11±2.9；p<0.0001)。寻找临床相关的单侧味觉障碍，发现18例（13.3％）患有半味觉障碍的患者，但只有4人(30.8%)主观抱怨味觉功能障碍。关于VS,KoosIV肿块在患侧得分最低(平均得分，7.5±3.7)。6例患者出现面部麻痹。面部麻痹不会导致较低的味觉评分（p=0.23）。
结论：在任何CPA大规模治疗之前，许多患者存在可测量的同侧味觉功能下降。大多数患者没有注意到这种预先存在的味觉障碍。从法医学的角度来看，这值得考虑。为了避免术后对味觉功能的要求，术前评估可以考虑.
