Abstract：
SignalP ( https://services.healthtech.dtu.dk/services/SignalP-6.0/ ) is a very popular prediction method for signal peptides, the intrinsic signals that make proteins secretory. The SignalP web server has existed since 1995 and is now in its sixth major version. In this historical account, we (three authors who have taken part in the entire journey plus the first author of the latest version) describe the differences between the versions and discuss the various decisions taken along the way.
摘要：
SignalP(https://services。healthtech.dtu.dk/services/SignalP-6.0/)是一种非常流行的信号肽预测方法，使蛋白质分泌的内在信号。SignalPWeb服务器自1995年以来一直存在，现在是其第六个主要版本。在这个历史账户中，我们（参与整个旅程的三位作者以及最新版本的第一作者）描述了版本之间的差异，并讨论了沿途的各种决定。
