Abstract：
Primary total knee arthroplasty (TKA) in patients under 50 is becoming more common. The goal of this study was to identify the diagnoses and predisposing factors for TKA prior to age 50. The Military Data Repository was queried for patients undergoing TKA prior to age 50. The cohort was matched to older patients. A total of 1,504 patients underwent manual record review for demographics, prior knee surgery, and indication for TKA. Primary osteoarthritis was the most common indication in both cohorts. Posttraumatic osteoarthritis was more common in patients who underwent TKA before age 50 (28%) compared with patients 50 and older (7%; p < 0.001). Patients who underwent TKA before age 50 were more likely to have previous anterior cruciate ligament injury, or any previous ipsilateral knee surgery (p < 0.001). These data suggest an association between prior knee injury and age at time of TKA. (Journal of Surgical Orthopaedic Advances 33(2):072-076, 2024).
摘要：
50岁以下患者的初次全膝关节置换术（TKA）变得越来越普遍。这项研究的目的是确定50岁之前TKA的诊断和诱发因素。在军事数据存储库中查询了50岁之前接受TKA的患者。该队列与老年患者相匹配。共有1,504名患者接受了人口统计学的手动记录审查，之前的膝盖手术，和TKA的适应症。原发性骨关节炎是两个队列中最常见的适应症。与50岁及以上患者（7%；p<0.001）相比，50岁之前接受TKA的患者（28%）更常见创伤后骨关节炎。在50岁之前接受TKA的患者更有可能发生前交叉韧带损伤，或任何以前的同侧膝关节手术（p<0.001）。这些数据表明，膝关节损伤与TKA时的年龄之间存在关联。（外科骨科杂志进展33（2）：072-076，2024）。
