铁通过增强葡萄糖转运蛋白 GLUT3 在肝脏中的表达来调节细胞增殖.
关键词: AMPK CREB1 GLUT3 cell proliferation iron overload
Mesh : Cell Proliferation / drug effects Animals Humans Glucose Transporter Type 3 / metabolism genetics Hep G2 Cells Liver / metabolism drug effects pathology Mice Cyclic AMP Response Element-Binding Protein / metabolism Iron / metabolism Male AMP-Activated Protein Kinases / metabolism Quaternary Ammonium Compounds / pharmacology Ferric Compounds / pharmacology Mice, Inbred C57BL Signal Transduction / drug effects Carcinoma, Hepatocellular / metabolism pathology genetics AMP-Activated Protein Kinase Kinases / metabolism Liver Neoplasms / metabolism pathology genetics
来 源:
DOI:10.3390/cells13131147
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