PDF(Pubmed)
Abstract：
UNASSIGNED: The purpose of this investigation was to examine the potential association between non-alcoholic fatty liver disease (NAFLD) and adverse maternal and perinatal outcomes during pregnancy.
UNASSIGNED: Gaining insights into the effect of NAFLD on pregnancy outcomes is essential to ensure the health and well-being of mothers and infants.
UNASSIGNED: This prospective cohort study was conducted at Imam Khomeini and Razi hospitals of Ahvaz City in 2022. Totally, 180 pregnant women in the NAFLD group to 180 in the control group. In this study, a researcher-made checklist was used to collect the background information, medical history, and lab data during their initial visit using. Follow-up continued until one week after delivery, with pregnancy outcomes assessed. Statistical analysis used student\'s t-test and the Chi-Square test for group comparisons.
UNASSIGNED: Significant differences were observed between the NAFLD, and control groups in terms of age (P=0.003), BMI (P=0.016), ALT and AST measures (P<0.001), and hypertensive complications (P=0.044). The NAFLD group had higher rates of gestational diabetes (P<0.001) and gestational hypertension (P=0.003). However, no significant differences were found in gestational age at delivery, early postpartum hemorrhage rates, birth weight, and neonatal Apgar scores (P>0.05).
UNASSIGNED: The pregnant women with NAFLD may be at risk for various complications during pregnancy, including a higher prevalence of gestational diabetes, elevated liver enzymes, and higher blood pressure compared to healthy pregnant women. However, the research failed to identify any statistically significant disparities between infants born to mothers with NAFLD and those delivered to healthy mothers in relation to birth weight, Apgar scores, or neonatal mortality.
UNASSIGNED: Gaining insights into the effect of NAFLD on pregnancy outcomes is essential to ensure the health and well-being of mothers and infants.
UNASSIGNED: This prospective cohort study was conducted at Imam Khomeini and Razi hospitals of Ahvaz City in 2022. Totally, 180 pregnant women in the NAFLD group to 180 in the control group. In this study, a researcher-made checklist was used to collect the background information, medical history, and lab data during their initial visit using. Follow-up continued until one week after delivery, with pregnancy outcomes assessed. Statistical analysis used student\'s t-test and the Chi-Square test for group comparisons.
UNASSIGNED: Significant differences were observed between the NAFLD, and control groups in terms of age (P=0.003), BMI (P=0.016), ALT and AST measures (P<0.001), and hypertensive complications (P=0.044). The NAFLD group had higher rates of gestational diabetes (P<0.001) and gestational hypertension (P=0.003). However, no significant differences were found in gestational age at delivery, early postpartum hemorrhage rates, birth weight, and neonatal Apgar scores (P>0.05).
UNASSIGNED: The pregnant women with NAFLD may be at risk for various complications during pregnancy, including a higher prevalence of gestational diabetes, elevated liver enzymes, and higher blood pressure compared to healthy pregnant women. However, the research failed to identify any statistically significant disparities between infants born to mothers with NAFLD and those delivered to healthy mothers in relation to birth weight, Apgar scores, or neonatal mortality.
摘要：
本研究的目的是检查非酒精性脂肪性肝病（NAFLD）与妊娠期不良母婴结局之间的潜在关联。
■深入了解NAFLD对妊娠结局的影响对于确保母亲和婴儿的健康和福祉至关重要。
■这项前瞻性队列研究于2022年在阿瓦士市的伊玛目霍梅尼和拉齐医院进行。完全正确,NAFLD组孕妇180例，对照组孕妇180例。在这项研究中,使用研究人员制作的清单来收集背景信息，病史,和实验室数据在他们初次访问期间使用。随访持续到分娩后一周，评估妊娠结局。统计学分析采用学生t检验和卡方检验进行分组比较。
■观察到NAFLD之间的显着差异，和对照组的年龄（P=0.003），BMI(P=0.016),ALT和AST测量（P<0.001），高血压并发症(P=0.044)。NAFLD组妊娠期糖尿病（P<0.001）和妊娠期高血压（P=0.003）的发生率更高。然而,分娩时的胎龄没有发现显著差异，早期产后出血率，出生体重,新生儿Apgar评分(P>0.05)。
患有NAFLD的孕妇在怀孕期间可能有各种并发症的风险，包括妊娠期糖尿病的患病率较高，肝酶升高，与健康孕妇相比，血压更高。然而,该研究未能确定NAFLD母亲所生的婴儿与健康母亲在出生体重方面的任何统计学差异，阿普加得分,或新生儿死亡率。
■深入了解NAFLD对妊娠结局的影响对于确保母亲和婴儿的健康和福祉至关重要。
■这项前瞻性队列研究于2022年在阿瓦士市的伊玛目霍梅尼和拉齐医院进行。完全正确,NAFLD组孕妇180例，对照组孕妇180例。在这项研究中,使用研究人员制作的清单来收集背景信息，病史,和实验室数据在他们初次访问期间使用。随访持续到分娩后一周，评估妊娠结局。统计学分析采用学生t检验和卡方检验进行分组比较。
■观察到NAFLD之间的显着差异，和对照组的年龄（P=0.003），BMI(P=0.016),ALT和AST测量（P<0.001），高血压并发症(P=0.044)。NAFLD组妊娠期糖尿病（P<0.001）和妊娠期高血压（P=0.003）的发生率更高。然而,分娩时的胎龄没有发现显著差异，早期产后出血率，出生体重,新生儿Apgar评分(P>0.05)。
患有NAFLD的孕妇在怀孕期间可能有各种并发症的风险，包括妊娠期糖尿病的患病率较高，肝酶升高，与健康孕妇相比，血压更高。然而,该研究未能确定NAFLD母亲所生的婴儿与健康母亲在出生体重方面的任何统计学差异，阿普加得分,或新生儿死亡率。
