关键词: acute ischemic stroke basilar artery occlusion comprehensive stroke center endovascular treatment weekend effect

来  源:   DOI:10.3389/fneur.2024.1413557   PDF(Pubmed)

Abstract:
UNASSIGNED: This study aimed to evaluate whether the \"weekend effect\" would affect the time metrics and the prognosis of acute ischemic stroke (AIS) patients who underwent endovascular treatment (EVT) due to basilar artery occlusion (BAO).
UNASSIGNED: Clinical data of AIS patients who underwent EVT due to BAO between December 2019 and July 2023 were retrospectively analyzed. At the time when the patients were admitted, the study population was divided into the weekdays daytime group and weekends nighttime group. In the subgroup analysis, the study cohort was divided into four groups: the weekdays daytime group, weekdays nighttime group, weekend daytime group, and weekend nighttime group. A good outcome was defined as a modified Rankin Scale score of ≤3 at 90 days after EVT. Time metrics [e.g. onset-to-door time (ODT) and door-to-puncture time (DPT)] and clinical outcomes were compared using appropriate statistical methods.
UNASSIGNED: A total of 111 patients (88 male patients, mean age, 67.7 ± 11.7 years) were included. Of these, 37 patients were treated during weekdays daytime, while 74 patients were treated during nights or weekends. There were no statistically significant differences in ODT (P = 0.136), DPT (P = 0.931), and also clinical outcomes (P = 0.826) between the two groups. Similarly, we found no significant differences in the time metrics and clinical outcomes among the four sub-groups (all P > 0.05).
UNASSIGNED: This study did not reveal any influence of the \"weekend effect\" on the time metrics and clinical outcomes in AIS patients who underwent EVT due to BAO at a comprehensive stroke center.
摘要:
本研究旨在评估“周末效应”是否会影响因基底动脉闭塞(BAO)而接受血管内治疗(EVT)的急性缺血性卒中(AIS)患者的时间指标和预后。
回顾性分析2019年12月至2023年7月因BAO而接受EVT的AIS患者的临床数据。在病人入院时,研究人群分为工作日白天组和周末夜间组。在亚组分析中,研究队列分为四组:工作日白天组,工作日夜间小组,周末白天组,和周末夜间小组。良好的结果定义为EVT后90天的改良Rankin量表评分≤3。使用适当的统计方法比较了时间指标[例如开始到门时间(ODT)和门到穿刺时间(DPT)]和临床结果。
共有111名患者(88名男性患者,平均年龄,包括67.7±11.7年)。其中,37例患者在工作日白天接受治疗,而74名患者在夜间或周末接受治疗。ODT差异无统计学意义(P=0.136)。DPT(P=0.931),两组之间的临床结果(P=0.826)。同样,我们发现4个亚组的时间指标和临床结局无显著差异(均P>0.05).
本研究未揭示“周末效应”对在综合卒中中心因BAO而接受EVT的AIS患者的时间指标和临床结局的影响。
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