PDF(Pubmed)
Abstract：
BACKGROUND: Intracranial arterial narrowing is a significant factor leading to brief episodes of reduced blood flow to the brain, known as transient ischemic attacks, or full-blown strokes. While atherosclerosis is commonly associated with intracranial arterial narrowing, it is frequently of a non-atherosclerotic nature in younger patients.
METHODS: Here, we present the case of a young stroke patient with narrowing of the middle cerebral artery (MCA), characterized as non-atherosclerotic lesions, who experienced an ischemic stroke despite receiving standard drug therapy. The patient underwent digital subtraction angiography (DSA) to assess the entire network of blood vessels in the brain, revealing significant narrowing (approximately 80%) in the M1 segment of the right MCA. Subsequently, the patient underwent Drug-Coated Balloon Angioplasty to treat the stenosis in the right MCA\'s M1 segment. Follow-up DSA confirmed the resolution of stenosis in this segment. Although the remaining branches showed satisfactory blood flow, the vessel wall exhibited irregularities. A review of DSA conducted six months later showed no evident stenosis in the right MCA, with a smooth vessel wall.
CONCLUSIONS: The use of drug-coated balloon angioplasty demonstrated favorable outcomes in repairing and reshaping the blood vessel wall in young patients. Therefore, it may be considered a promising treatment option for similar cases.
METHODS: Here, we present the case of a young stroke patient with narrowing of the middle cerebral artery (MCA), characterized as non-atherosclerotic lesions, who experienced an ischemic stroke despite receiving standard drug therapy. The patient underwent digital subtraction angiography (DSA) to assess the entire network of blood vessels in the brain, revealing significant narrowing (approximately 80%) in the M1 segment of the right MCA. Subsequently, the patient underwent Drug-Coated Balloon Angioplasty to treat the stenosis in the right MCA\'s M1 segment. Follow-up DSA confirmed the resolution of stenosis in this segment. Although the remaining branches showed satisfactory blood flow, the vessel wall exhibited irregularities. A review of DSA conducted six months later showed no evident stenosis in the right MCA, with a smooth vessel wall.
CONCLUSIONS: The use of drug-coated balloon angioplasty demonstrated favorable outcomes in repairing and reshaping the blood vessel wall in young patients. Therefore, it may be considered a promising treatment option for similar cases.
摘要：
背景：颅内动脉狭窄是导致短暂的脑血流量减少的重要因素，称为短暂性脑缺血发作，或全面的中风。虽然动脉粥样硬化通常与颅内动脉狭窄有关，在年轻患者中，它通常具有非动脉粥样硬化性质。
方法：这里，我们介绍了一个年轻的中风患者，大脑中动脉（MCA）狭窄，表现为非动脉粥样硬化病变,尽管接受了标准药物治疗，但仍经历了缺血性中风。患者接受了数字减影血管造影（DSA）以评估大脑中的整个血管网络，显示右侧MCAM1段明显变窄(约80%)。随后，患者接受药物涂层球囊血管成形术治疗右侧MCAM1段狭窄。随访DSA证实该节段狭窄的消退。尽管其余分支显示出令人满意的血流，血管壁显示不规则。6个月后进行的DSA检查显示右侧MCA无明显狭窄,有一个光滑的血管壁。
结论：使用药物涂层球囊血管成形术在年轻患者的血管壁修复和重塑中显示出良好的结果。因此,它可能被认为是类似病例的一种有希望的治疗选择.
方法：这里，我们介绍了一个年轻的中风患者，大脑中动脉（MCA）狭窄，表现为非动脉粥样硬化病变,尽管接受了标准药物治疗，但仍经历了缺血性中风。患者接受了数字减影血管造影（DSA）以评估大脑中的整个血管网络，显示右侧MCAM1段明显变窄(约80%)。随后，患者接受药物涂层球囊血管成形术治疗右侧MCAM1段狭窄。随访DSA证实该节段狭窄的消退。尽管其余分支显示出令人满意的血流，血管壁显示不规则。6个月后进行的DSA检查显示右侧MCA无明显狭窄,有一个光滑的血管壁。
结论：使用药物涂层球囊血管成形术在年轻患者的血管壁修复和重塑中显示出良好的结果。因此,它可能被认为是类似病例的一种有希望的治疗选择.
