PDF(Pubmed)
Abstract：
UNASSIGNED: The OI was originally evaluated as a prognostic tool for acute hypoxemic respiratory failure in children and was an independent predictor for mortality in adult patients with acute respiratory distress syndrome (ARDS).
UNASSIGNED: Oxygenation index and OSI of 201 adult patients undergoing emergency surgery were evaluated at different time points. The primary objective of this study was to find the correlation between OI and OSI. The secondary objectives were to find the prognostic utility of OI and OSI for postoperative mechanical ventilation and mortality.
UNASSIGNED: Significant statistical correlation was found between OI and OSI both at the beginning (r 2 = 0.61; p < 0.001) and immediately after surgery (r 2 = 0.47; p < 0.001). Oxygen saturation index at the beginning [area under the receiver operating characteristics curve (AUROC) (95% CI) 0.76 (0.62-0.89); best cutoff 3.9, sensitivity 64% and specificity 45%] and immediately after surgery [AUROC (95% CI) 0.82 (0.72-0.92); best cutoff 3.57, sensitivity 79%, and specificity 62%] were reasonable predictors of the requirement of invasive ventilatory support. Exploratory analysis reported that older age (p = 0.02), higher total leukocyte count (p = 0.002), higher arterial lactate (p = 0.02), and higher driving pressure (p < 0.001) were independently associated with hospital mortality.
UNASSIGNED: In adult patients undergoing emergency laparotomy under general anesthesia, OI and OSI were found to be correlated. Both metrics demonstrated reasonable accuracy in predicting the need for invasive ventilatory support beyond 24 hours and hospital mortality.
UNASSIGNED: Thakuria R, Ernest EE, Chowdhury AR, Pangasa N, Kayina CA, Bhattacharjee S, et al. Oxygenation Index and Oxygen Saturation Index for Predicting Postoperative Outcome in Patients Undergoing Emergency Surgery: A Prospective Cohort Study. Indian J Crit Care Med 2024;28(7):645-649.
UNASSIGNED: Oxygenation index and OSI of 201 adult patients undergoing emergency surgery were evaluated at different time points. The primary objective of this study was to find the correlation between OI and OSI. The secondary objectives were to find the prognostic utility of OI and OSI for postoperative mechanical ventilation and mortality.
UNASSIGNED: Significant statistical correlation was found between OI and OSI both at the beginning (r 2 = 0.61; p < 0.001) and immediately after surgery (r 2 = 0.47; p < 0.001). Oxygen saturation index at the beginning [area under the receiver operating characteristics curve (AUROC) (95% CI) 0.76 (0.62-0.89); best cutoff 3.9, sensitivity 64% and specificity 45%] and immediately after surgery [AUROC (95% CI) 0.82 (0.72-0.92); best cutoff 3.57, sensitivity 79%, and specificity 62%] were reasonable predictors of the requirement of invasive ventilatory support. Exploratory analysis reported that older age (p = 0.02), higher total leukocyte count (p = 0.002), higher arterial lactate (p = 0.02), and higher driving pressure (p < 0.001) were independently associated with hospital mortality.
UNASSIGNED: In adult patients undergoing emergency laparotomy under general anesthesia, OI and OSI were found to be correlated. Both metrics demonstrated reasonable accuracy in predicting the need for invasive ventilatory support beyond 24 hours and hospital mortality.
UNASSIGNED: Thakuria R, Ernest EE, Chowdhury AR, Pangasa N, Kayina CA, Bhattacharjee S, et al. Oxygenation Index and Oxygen Saturation Index for Predicting Postoperative Outcome in Patients Undergoing Emergency Surgery: A Prospective Cohort Study. Indian J Crit Care Med 2024;28(7):645-649.
摘要：
■OI最初被评估为儿童急性低氧性呼吸衰竭的预后工具，并且是成人急性呼吸窘迫综合征（ARDS）患者死亡率的独立预测因子。
■在不同时间点评估了201例接受急诊手术的成年患者的氧合指数和OSI。这项研究的主要目的是发现OI和OSI之间的相关性。次要目标是发现OI和OSI对术后机械通气和死亡率的预后效用。
■在手术开始时（r2=0.61；p<0.001）和术后即刻（r2=0.47；p<0.001）发现OI和OSI之间存在显着的统计学相关性。开始时的氧饱和度指数[接受者工作特征曲线下面积（AUROC）（95％CI）0.76（0.62-0.89）；最佳截止值3.9，灵敏度64％和特异性45％]以及术后立即[AUROC（95％CI）0.82（0.72-0.92）；最佳截止值3.57，灵敏度79％，和特异性62%]是侵入性通气支持需求的合理预测因子。探索性分析报告年龄较大(p=0.02)，白细胞总数较高（p=0.002），较高的动脉乳酸（p=0.02），较高的驱动压(p<0.001)与住院死亡率独立相关.
■在全身麻醉下进行紧急剖腹手术的成年患者中，发现OI和OSI是相关的。这两个指标在预测超过24小时的有创通气支持需求和医院死亡率方面都显示出合理的准确性。
■ThakuriaR,欧内斯特EE,ChowdhuryAR,PangasaN,KayinaCA,BhattacharjeeS,etal.氧合指数和氧饱和度指数预测急诊手术患者术后结局：一项前瞻性队列研究。印度J暴击护理中心2024；28（7）：645-649。
■在不同时间点评估了201例接受急诊手术的成年患者的氧合指数和OSI。这项研究的主要目的是发现OI和OSI之间的相关性。次要目标是发现OI和OSI对术后机械通气和死亡率的预后效用。
■在手术开始时（r2=0.61；p<0.001）和术后即刻（r2=0.47；p<0.001）发现OI和OSI之间存在显着的统计学相关性。开始时的氧饱和度指数[接受者工作特征曲线下面积（AUROC）（95％CI）0.76（0.62-0.89）；最佳截止值3.9，灵敏度64％和特异性45％]以及术后立即[AUROC（95％CI）0.82（0.72-0.92）；最佳截止值3.57，灵敏度79％，和特异性62%]是侵入性通气支持需求的合理预测因子。探索性分析报告年龄较大(p=0.02)，白细胞总数较高（p=0.002），较高的动脉乳酸（p=0.02），较高的驱动压(p<0.001)与住院死亡率独立相关.
■在全身麻醉下进行紧急剖腹手术的成年患者中，发现OI和OSI是相关的。这两个指标在预测超过24小时的有创通气支持需求和医院死亡率方面都显示出合理的准确性。
■ThakuriaR,欧内斯特EE,ChowdhuryAR,PangasaN,KayinaCA,BhattacharjeeS,etal.氧合指数和氧饱和度指数预测急诊手术患者术后结局：一项前瞻性队列研究。印度J暴击护理中心2024；28（7）：645-649。
