OBJECTIVE: To address this problem by employing bibliometric tools to explore the publication years, countries/regions, institutions, journals, authors, keywords, and references in this field.
METHODS: The literature was collected from Web of Science databases. CiteSpace-6.2R4, a widely used bibliometric analysis software package, was used for institutional analysis and reference burst analysis. VOSviewer 1.6.19 was used for journal co-citation analysis, author co-authorship and co-citation analysis. The \'online platform for bibliometric analysis (https://bibliometric.com/app)\' was used to assess the total number of publications and the cooperation relationships between countries. Finally, we employed the bibliometric R software package (version R.4.3.1) in R-studio, for a comprehensive scientific analysis of the literature.
RESULTS: Our analysis included a total of 1466 publications, revealing a significant yearly increase in articles on the study of gastrointestinal tumor organoids. The United States (n = 393) and Helmholtz Association (n = 93) have emerged as the leading countries and institutions, respectively, in this field, with Hans Clevers and Toshiro Sato being the most contributing authors. The most influential journal in this field is Gastroenterology. The most impactful reference is \"Long term expansion of epithelial organs from human colon, adenoma, adenocarcinoma, and Barrett\'s epithelium\". Keywords analysis and citation burst analysis indicate that precision medicine, disease modeling, drug development and screening, and regenerative medicine are the most cutting-edge directions. These focal points were further detailed based on the literature.
CONCLUSIONS: This bibliometric study offers an objective and quantitative analysis of the research in this field, which can be considered as an important guide for next scientific research.
目的:为了解决这个问题,采用文献计量学工具探索出版年份,国家/地区,机构,期刊,作者,关键词,以及该领域的参考文献。
方法:文献是从WebofScience数据库中收集的。CiteSpace-6.2R4,一个广泛使用的文献计量分析软件包,用于机构分析和参考突发性分析。VOSviewer1.6.19用于期刊共引分析,作者共同作者和共同引文分析。“文献计量分析在线平台(https://bibliometric.com/app)”用于评估出版物总数和国家之间的合作关系。最后,我们在R-studio中使用了文献计量R软件包(R.4.3.1版),对文献进行全面的科学分析。
结果:我们的分析包括1466种出版物,揭示了有关胃肠道肿瘤类器官研究的文章每年显着增加。美国(n=393)和亥姆霍兹协会(n=93)已成为主要国家和机构,分别,在这个领域,汉斯·克莱弗斯和佐藤敏郎是最有贡献的作者。该领域最有影响力的杂志是胃肠病学。最有影响力的参考文献是“人类结肠上皮器官的长期扩张,腺瘤,腺癌,和巴雷特的上皮。"关键词分析和引文爆发分析表明,精准医学,疾病建模,药物开发和筛选,再生医学是最尖端的方向。根据文献进一步详述了这些焦点。
结论:本文献计量学研究对该领域的研究提供了客观和定量的分析,这可以被认为是下一步科学研究的重要指南。