Abstract:
Introduction Heart failure (HF) represents a substantial global health concern, evidenced by its high prevalence, significant mortality rates, and considerable economic impact worldwide. Within this broader context, congestive heart failure (CHF) emerges as a critical subset, affecting millions and leading to high rates of morbidity and mortality. Recent explorations have started to uncover a potential link between kidney stones and broader systemic health problems, including coronary artery disease. This association suggests that kidney stones might also indicate an increased risk for cardiovascular diseases such as CHF. However, the exploration into the direct relationship between kidney stones and CHF is still in its nascent stages, creating a significant gap in understanding the full cardiovascular implications of kidney stone disease. Methods Utilizing data from the National Health and Nutrition Examination Survey (NHANES) for the period of March 2017 to March 2020, we conducted a logistic regression analysis to assess the relationship between kidney stones and CHF. This analysis adjusted for key variables such as age, gender, race, and educational attainment, aiming to isolate the impact of kidney stones on CHF risk among 8,521 participants. Results Our findings revealed a higher incidence of CHF among individuals with a history of kidney stones (7%) compared to those without (3%). Logistic regression analysis further highlighted kidney stones as an independent risk factor for CHF, with an odds ratio (OR) of 1.857, significant at p < 0.01. These results underline the importance of considering kidney stones in the broader context of cardiovascular health risks, particularly CHF, as their presence significantly elevates the risk compared to the general population without kidney stones. Additional demographic analyses indicated significant influences of age, gender, race, and educational level on the risk of CHF, emphasizing the complex interplay between these factors and heart health. Conclusion The study confirms the association between a history of kidney stones and an increased risk of CHF, suggesting the need for heightened cardiovascular monitoring for patients with such a history. It also brings to light the significant role demographic factors play in CHF risk, advocating for targeted interventions to mitigate these disparities. Our research supports a broader view of patient care that includes consideration of urological conditions as potential risk factors for heart failure. Further exploration into the mechanisms linking kidney stones and cardiovascular health is recommended to inform more effective prevention and treatment strategies.
摘要:
介绍心力衰竭(HF)代表了一个重大的全球健康问题,它的高患病率证明了这一点,显著的死亡率,和全球相当大的经济影响。在这个更广泛的背景下,充血性心力衰竭(CHF)是一个关键的子集,影响数百万人,导致高发病率和死亡率。最近的探索已经开始发现肾结石与更广泛的系统性健康问题之间的潜在联系。包括冠状动脉疾病.这种关联表明,肾结石也可能表明心血管疾病如CHF的风险增加。然而,对肾结石与CHF之间直接关系的探索仍处于起步阶段,在了解肾结石疾病的全部心血管影响方面创造了巨大的差距。方法利用2017年3月至2020年3月的国家健康与营养调查(NHANES)数据,我们进行了逻辑回归分析,以评估肾结石与CHF之间的关系。此分析针对关键变量进行了调整,如年龄、性别,种族,和教育程度,旨在在8,521名参与者中分离肾结石对CHF风险的影响。结果我们的发现显示,有肾结石病史的人(7%)的CHF发生率高于无肾结石病史的人(3%)。Logistic回归分析进一步强调肾结石是CHF的独立危险因素。比值比(OR)为1.857,p<0.01时显著。这些结果强调了在更广泛的心血管健康风险背景下考虑肾结石的重要性。特别是CHF,与没有肾结石的普通人群相比,它们的存在显着提高了风险。额外的人口统计学分析表明年龄的显著影响,性别,种族,和教育水平对CHF的风险,强调这些因素与心脏健康之间复杂的相互作用。结论该研究证实了肾结石病史与CHF风险增加之间的关联。提示有此类病史的患者需要加强心血管监测.它还揭示了人口因素在CHF风险中的重要作用,倡导有针对性的干预措施,以减轻这些差距。我们的研究支持更广泛的患者护理观点,包括将泌尿外科疾病视为心力衰竭的潜在危险因素。建议进一步探索肾结石与心血管健康之间的联系机制,以提供更有效的预防和治疗策略。