UNASSIGNED: Data were obtained from the Korean Association for Lung Cancer Registry (KALC-R), a database created using a retrospective sampling survey by the Korean Central Cancer Registry (KCCR) and the Lung Cancer Registration Committee.
UNASSIGNED: A total of 3,176 patients who underwent curative resection was evaluated. The mean observation time was approximately 35.4 months. Among stage I to IIIA NSCLC patients, the EGFR-mutant subgroup included 867 patients, and 75.2%, 11.2%, and 11.8% were classified as stage I, stage II, and stage III, respectively. Within the EGFR-mutant subgroup, 44 (5.1%) and 121 (14.0%) patients showed early and late recurrence, respectively. Multivariate analysis on association with postoperative relapse among the EGFR-mutant subgroup showed that age, pathologic N and TNM stages, pleural invasion status, and surgery type were independent significant factors.
UNASSIGNED: Among the population that underwent complete resection for early NSCLC with EGFR mutation, patients with advanced stage, pleural invasion, or limited resection are more likely to show postoperative relapse.
■数据来自韩国肺癌登记协会(KALC-R),通过韩国中央癌症登记处(KCCR)和肺癌登记委员会的回顾性抽样调查建立的数据库.
■总共评估了3,176例接受根治性切除术的患者。平均观察时间约为35.4个月。在I至IIIA期NSCLC患者中,EGFR突变亚组包括867例患者,75.2%,11.2%,11.8%被归类为第一阶段,第二阶段,第三阶段,分别。在EGFR突变亚组中,44例(5.1%)和121例(14.0%)患者出现早期和晚期复发,分别。EGFR突变亚组患者的年龄与术后复发相关的多因素分析显示,病理N和TNM分期,胸膜浸润状态,和手术类型是独立的显著影响因素。
■在接受EGFR突变的早期NSCLC完全切除的人群中,晚期患者,胸膜侵犯,或有限的切除更有可能显示术后复发。