Abstract：
The effect of paternal age on fertility remains unclear. This retrospective study aims to examine the impact of male age on semen parameters and the reproductive outcomes of men admitted to an infertility center over a 9-year period. A total of 8046 patients were included in the study. Men were divided into four age groups. The groups were evaluated for semen parameters and reproductive outcome. The 21-30 year group presented lower sperm concentrations in comparison to those aged 31-40 and 41-50, yet shared a similar concentration to those over 50 years of age. Moreover, grades A and B decreased significantly in men aged over 50 years. The highest progressive motility and normozoospermia were observed in the age group 31-40 years while men over 50 years of age had the highest rates of asthenozoospermia and oligoasthenozoospermia. Furthermore, live birth results were reported in 5583 of the patients who underwent intracytoplasmic sperm injection (ICSI) and were found highest between 31-40 years of age. To our knowledge, this is the largest study in Turkey focusing on male age-related semen parameters and ICSI pregnancy outcomes. The study demonstrates that age is a significant factor for semen quality and live birth.
摘要：
父亲年龄对生育能力的影响尚不清楚。这项回顾性研究旨在研究男性年龄对精液参数的影响以及在9年内进入不育中心的男性的生殖结果。共有8046名患者被纳入研究。男性分为四个年龄组。评估各组的精液参数和生殖结果。与31-40岁和41-50岁的人相比，21-30岁组的精子浓度较低，但与50岁以上的人的精子浓度相似。此外，50岁以上男性的A级和B级显著下降。在31-40岁的年龄组中观察到最高的进行性运动和正常精子症，而50岁以上的男性弱精子症和少弱精子症的发生率最高。此外，在接受卵胞浆内单精子注射(ICSI)的患者中,有5583例报告了活产结果,发现年龄在31-40岁之间最高.据我们所知,这是土耳其最大规模的研究,重点关注男性年龄相关精液参数和ICSI妊娠结局.研究表明，年龄是精液质量和活产的重要因素。
