PDF(Pubmed)
Abstract：
BACKGROUND: Parental history of diabetes is an established risk factor for type 2 diabetes mellitus (T2DM). There is limited data on the association of parental history with the prevalence of T2DM in Sri Lanka. The study aims to examine the prevalence and correlation of parental history and factors such as the onset age, glycaemic control, and self-reported dietary compliance among T2DM patients. With a rising incidence of T2DM in Sri Lanka, understanding the impact of parental history on age at diagnosis and glycemic control can aid in targeted screening and interventions.
METHODS: A cross-sectional study was carried out on 500 T2DM patients attending a diabetes clinic in Galle, the capital of Southern Sri Lanka with a multiethnic population. Convenient sampling strategy was followed in the recruitment process and a questionnaire-based method was used to collect the data. All the collected data was analysed using SPSS V 25.0.
RESULTS: 51.2% had a parental history of T2DM, and those with a positive parental history were diagnosed six years earlier than those with a negative parental history (p < 0.001). A significant correlation between parental history and gestational diabetes mellitus (GDM) was observed (p < 0.001). Patients with a parental history reported better dietary adherence (p < 0.001). Binary logistic regression analysis revealed patients with positive parental history had significantly lower HbA1C (p = 0.003, OR = 0.748).
CONCLUSIONS: T2DM patients with a parental history showed significant association with early diabetes onset, GDM, better glycemic control, and dietary adherence.
METHODS: A cross-sectional study was carried out on 500 T2DM patients attending a diabetes clinic in Galle, the capital of Southern Sri Lanka with a multiethnic population. Convenient sampling strategy was followed in the recruitment process and a questionnaire-based method was used to collect the data. All the collected data was analysed using SPSS V 25.0.
RESULTS: 51.2% had a parental history of T2DM, and those with a positive parental history were diagnosed six years earlier than those with a negative parental history (p < 0.001). A significant correlation between parental history and gestational diabetes mellitus (GDM) was observed (p < 0.001). Patients with a parental history reported better dietary adherence (p < 0.001). Binary logistic regression analysis revealed patients with positive parental history had significantly lower HbA1C (p = 0.003, OR = 0.748).
CONCLUSIONS: T2DM patients with a parental history showed significant association with early diabetes onset, GDM, better glycemic control, and dietary adherence.
摘要：
背景：父母糖尿病史是2型糖尿病（T2DM）的既定危险因素。关于父母病史与斯里兰卡T2DM患病率的关联的数据有限。该研究旨在检查父母病史和发病年龄等因素的患病率和相关性，血糖控制，2型糖尿病患者的饮食依从性和自我报告。随着斯里兰卡T2DM发病率的上升，了解父母病史对诊断年龄和血糖控制的影响有助于有针对性的筛查和干预.
方法：对加勒糖尿病诊所就诊的500名T2DM患者进行了横断面研究，斯里兰卡南部的首都，拥有多民族人口。在招聘过程中遵循便利的抽样策略，并使用基于问卷的方法收集数据。所有收集的数据使用SPSSV25.0进行分析。
结果：51.2%的父母有T2DM病史，父母史阳性的患者比父母史阴性的患者早6年被确诊(p<0.001).父母病史与妊娠期糖尿病（GDM）之间存在显着相关性（p<0.001）。有父母病史的患者报告了更好的饮食依从性（p<0.001）。二元logistic回归分析显示，父母病史阳性的患者HbA1C明显降低（p=0.003，OR=0.748）。
结论：有父母病史的T2DM患者与早期糖尿病发病显著相关，GDM,更好的血糖控制，和饮食依从性。
方法：对加勒糖尿病诊所就诊的500名T2DM患者进行了横断面研究，斯里兰卡南部的首都，拥有多民族人口。在招聘过程中遵循便利的抽样策略，并使用基于问卷的方法收集数据。所有收集的数据使用SPSSV25.0进行分析。
结果：51.2%的父母有T2DM病史，父母史阳性的患者比父母史阴性的患者早6年被确诊(p<0.001).父母病史与妊娠期糖尿病（GDM）之间存在显着相关性（p<0.001）。有父母病史的患者报告了更好的饮食依从性（p<0.001）。二元logistic回归分析显示，父母病史阳性的患者HbA1C明显降低（p=0.003，OR=0.748）。
结论：有父母病史的T2DM患者与早期糖尿病发病显著相关，GDM,更好的血糖控制，和饮食依从性。
