关键词: Clouston syndrome Hidrotic ectodermal dysplasia botanical extracts case report congenital alopecia

Mesh : Humans Minoxidil Male Child Plant Extracts / administration & dosage Alopecia / drug therapy pathology Ectodermal Dysplasia / drug therapy genetics pathology Drug Therapy, Combination Mutation Treatment Outcome Connexins / genetics

来  源:   DOI:10.1080/09546634.2024.2378163

Abstract:
UNASSIGNED: We aim to explore a potential treatment strategy for hair loss.
UNASSIGNED: A male 6-year-old child was diagnosed with hidrotic ectodermal dysplasia 2 (HED2) caused by GJB6 (p.G11R) mutations. He presented at our clinic with diffuse thinning and fine and brittle hair since birth. Additionally, the child exhibited abnormal development of teeth, fingernails, and toenails. The condition of the child\'s hair had not improved significantly with age. He was treated with botanical extracts combined with Minoxidil.
UNASSIGNED: After one and a half months of treatment, the patient showed remarkable hair growth.
UNASSIGNED: Our team has previously used botanical extracts in combination for the treatment of autosomal recessive wooly hair in children. In the present case, treatment with botanical extract combined with minoxidil was found to be equally efficacious. This case report provides valuable information for future studies on the use of botanical extracts in treating hair loss, as well as a safe and effective potential treatment strategy for children with congenital alopecia.
摘要:
我们的目标是探索一种潜在的脱发治疗策略。
一名6岁的男性儿童被诊断为由GJB6引起的多汗性外胚层发育不良2(HED2)(p。G11R)突变。自出生以来,他在我们的诊所出现了弥漫的稀疏和细而脆的头发。此外,孩子表现出牙齿发育异常,手指甲,和脚趾甲.孩子的头发状况并没有随着年龄的增长而明显改善。他接受了植物提取物与米诺地尔的联合治疗。
经过一个半月的治疗,病人头发明显生长。
我们的团队先前已将植物提取物联合用于治疗儿童常染色体隐性毛发。在目前的情况下,发现植物提取物与米诺地尔联合治疗同样有效。本病例报告为今后使用植物提取物治疗脱发的研究提供了有价值的信息,以及儿童先天性脱发安全有效的潜在治疗策略。
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