Abstract：
Xanthomonas oryzae pv. oryzae (Xoo), the causative agent of bacterial blight (BB), has developed a unique strategy to infect rice by hijacking the host\'s methylglyoxal (MG) detoxification pathway. This results in an over-accumulation of MG, which facilitates tissue colonization and evasion of host\'s immune responses. While MG role in abiotic stresses is well-documented, its involvement in biotic stresses has not been extensively explored. Recently, Fu et al. (2024) provided the first evidence of MG role in promoting Xoo pathogenesis in rice. This new virulence strategy contributes to the pathogen\'s remarkable adaptability and survival. In this mechanism of hijacking of MG detoxification pathway, Xoo induces OsWRKY62.1 to inhibit OsGLY II expression, leading to MG overaccumulation in infected rice cells. This excess MG hinders plant cell organelle function, creating a favorable environment for Xoo by compromising the rice defense system. In this article, we have presented our perspectives on how the BB pathogen adapts its virulence mechanisms to infect and cause disease in rice.
摘要：
米黄单胞菌pv。稻米（Xoo），细菌性疫病（BB）的病原体，开发了一种独特的策略，通过劫持宿主的甲基乙二醛（MG）解毒途径感染水稻。这导致MG的过度积累，这有助于组织定植和逃避宿主的免疫反应。虽然MG在非生物胁迫中的作用是有据可查的，它在生物应激中的参与尚未得到广泛的探索。最近,Fuetal.（2024）提供了MG在促进水稻Xoo发病中的作用的第一个证据。这种新的毒力策略有助于病原体显著的适应性和存活。在这一劫持MG解毒途径的机制中，Xoo诱导OsWRKY62.1抑制OsGLYII表达，导致MG在受感染的水稻细胞中过度积累。这种过量的MG阻碍了植物细胞器的功能，通过破坏水稻防御系统为Xoo创造有利的环境。在这篇文章中,我们已经提出了关于BB病原体如何适应其毒力机制以感染和引起水稻疾病的观点。
