Abstract：
OBJECTIVE: To assess the thickness of each layer of the gallbladder wall with different diseases in dogs.
METHODS: 72 gallbladders.
METHODS: Retrospective study of dogs that underwent cholecystectomy. Histopathological specimens of the gallbladders were reviewed. Histopathological diagnosis was made as gallbladder mucocele or cholecystitis, and cholecystitis was further categorized into chronic cholecystitis, acute-on-chronic cholecystitis, acute cholecystitis, and necrotic cholecystitis. The thickness of each layer of the gallbladder wall was measured.
RESULTS: 22 dogs were diagnosed with gallbladder mucocele without cholecystitis, 24 with gallbladder mucocele and cholecystitis, 20 with only cholecystitis, and 6 as normal. Histopathological subclassification of cholecystitis in 44 gallbladders led to diagnosis of chronic cholecystitis in 21 gallbladders, acute-on-chronic cholecystitis in 10 gallbladders, acute cholecystitis in 6 gallbladders, and necrotic cholecystitis in 7 gallbladders. The thickness of the entire wall of the gallbladder (P < .0001) and the thickness of the mucosa (P < .0001) and subserosa (P < .0001) were affected by the different disease processes.
CONCLUSIONS: Layers of the gallbladder wall were affected by diseases present in the gallbladder. It resulted in a difference in the thickness of the wall of the gallbladder among the gallbladder diseases in this study. Histopathological changes should be taken into consideration before surgery while deciding what technique to use to perform a cholecystectomy.
METHODS: 72 gallbladders.
METHODS: Retrospective study of dogs that underwent cholecystectomy. Histopathological specimens of the gallbladders were reviewed. Histopathological diagnosis was made as gallbladder mucocele or cholecystitis, and cholecystitis was further categorized into chronic cholecystitis, acute-on-chronic cholecystitis, acute cholecystitis, and necrotic cholecystitis. The thickness of each layer of the gallbladder wall was measured.
RESULTS: 22 dogs were diagnosed with gallbladder mucocele without cholecystitis, 24 with gallbladder mucocele and cholecystitis, 20 with only cholecystitis, and 6 as normal. Histopathological subclassification of cholecystitis in 44 gallbladders led to diagnosis of chronic cholecystitis in 21 gallbladders, acute-on-chronic cholecystitis in 10 gallbladders, acute cholecystitis in 6 gallbladders, and necrotic cholecystitis in 7 gallbladders. The thickness of the entire wall of the gallbladder (P < .0001) and the thickness of the mucosa (P < .0001) and subserosa (P < .0001) were affected by the different disease processes.
CONCLUSIONS: Layers of the gallbladder wall were affected by diseases present in the gallbladder. It resulted in a difference in the thickness of the wall of the gallbladder among the gallbladder diseases in this study. Histopathological changes should be taken into consideration before surgery while deciding what technique to use to perform a cholecystectomy.
摘要：
目的：评估狗患有不同疾病的胆囊壁各层的厚度。
方法：72个胆囊。
方法：对接受胆囊切除术的狗进行回顾性研究。回顾了胆囊的组织病理学标本。组织病理学诊断为胆囊黏液囊肿或胆囊炎，胆囊炎被进一步归类为慢性胆囊炎，急性对慢性胆囊炎,急性胆囊炎,和坏死性胆囊炎.测量胆囊壁各层的厚度。
结果：22只狗被诊断为胆囊黏液囊肿而无胆囊炎，24伴有胆囊黏液囊肿和胆囊炎，20只患有胆囊炎，6和正常一样。44例胆囊胆囊炎的组织病理学分类导致21例胆囊慢性胆囊炎的诊断，10个胆囊急性对慢性胆囊炎，急性胆囊炎在6个胆囊，和7个胆囊坏死性胆囊炎。胆囊全壁厚度(P<.0001)、黏膜厚度(P<.0001)和浆膜下厚度(P<.0001)受不同疾病进程的影响。
结论：胆囊壁层受胆囊疾病的影响。在这项研究中，这导致了胆囊疾病之间胆囊壁厚度的差异。手术前应考虑组织病理学变化，同时决定使用哪种技术进行胆囊切除术。
方法：72个胆囊。
方法：对接受胆囊切除术的狗进行回顾性研究。回顾了胆囊的组织病理学标本。组织病理学诊断为胆囊黏液囊肿或胆囊炎，胆囊炎被进一步归类为慢性胆囊炎，急性对慢性胆囊炎,急性胆囊炎,和坏死性胆囊炎.测量胆囊壁各层的厚度。
结果：22只狗被诊断为胆囊黏液囊肿而无胆囊炎，24伴有胆囊黏液囊肿和胆囊炎，20只患有胆囊炎，6和正常一样。44例胆囊胆囊炎的组织病理学分类导致21例胆囊慢性胆囊炎的诊断，10个胆囊急性对慢性胆囊炎，急性胆囊炎在6个胆囊，和7个胆囊坏死性胆囊炎。胆囊全壁厚度(P<.0001)、黏膜厚度(P<.0001)和浆膜下厚度(P<.0001)受不同疾病进程的影响。
结论：胆囊壁层受胆囊疾病的影响。在这项研究中，这导致了胆囊疾病之间胆囊壁厚度的差异。手术前应考虑组织病理学变化，同时决定使用哪种技术进行胆囊切除术。
