Mesh : Animals Cattle Humans Birds / virology Cattle Diseases / epidemiology prevention & control virology Disease Outbreaks / prevention & control veterinary Influenza A Virus, H5N1 Subtype / pathogenicity Influenza in Birds / epidemiology transmission virology Orthomyxoviridae Infections / epidemiology prevention & control veterinary virology Poultry / virology United States / epidemiology

来  源:   DOI:10.1126/science.adr5866

Abstract:
The relentless march of a highly pathogenic avian influenza virus (HPAIV) strain, known as H5N1, to become an unprecedented panzootic continues unchecked. The leap of H5N1 clade 2.3.4.4b from Eurasia and Africa to North America in 2021 and its further spread to South America and the Antarctic have exposed new avian and mammalian populations to the virus and led to outbreaks on an unrivaled scale. The virus has infected wild birds across vast geographic regions and caused wildlife deaths in some of the world\'s most biodiverse ecosystems. Hundreds of millions of poultry have died or been culled, affecting global food security in some of the world\'s poorest regions. Numerous mammalian species, including sea lions and fur animals, have been infected. Outbreaks in dairy cows in the United States have been occurring for months, seemingly unchecked in most affected states. Why is there not a greater sense of urgency to control these infections?
摘要:
高致病性禽流感病毒(HPAIV)毒株的无情行进,被称为H5N1,成为前所未有的全动物继续不受控制。H5N1进化枝2.3.4.4b在2021年从欧亚大陆和非洲跃升到北美,并进一步传播到南美和南极,使新的鸟类和哺乳动物种群暴露于该病毒,并导致无与伦比的规模爆发。该病毒已经在广阔的地理区域感染了野生鸟类,并导致了世界上一些生物多样性最强的生态系统中的野生动物死亡。数以亿计的家禽死亡或被扑杀,影响世界上一些最贫穷地区的全球粮食安全。许多哺乳动物物种,包括海狮和毛皮动物,已经被感染了。美国奶牛的疫情已经持续数月,在大多数受影响的州似乎不受控制。为什么没有更大的紧迫感来控制这些感染?
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