PDF(Pubmed)
Abstract：
BACKGROUND: Social communication is a key factor in maintaining cognitive function and contributes to well-being in later life.
OBJECTIVE: This study will examine the effects of \"Photo-Integrated Conversation Moderated by Application version 2\" (PICMOA-2), which is a web-based conversational intervention, on cognitive performance, frailty, and social and psychological indicators among community-dwelling older adults.
METHODS: This study is a randomized controlled trial with an open-label, 2-parallel group trial and 1:1 allocation design. Community dwellers aged 65 years and older were enrolled in the trial and divided into the intervention and control groups. The intervention group receives the PICMOA-2 program, a web-based group conversation, once every 2 weeks for 6 months. The primary outcome is verbal fluency, including phonemic and semantic fluency. The secondary outcomes are other neuropsychiatric batteries, including the Mini-Mental State Examination, Logical Memory (immediate and delay), verbal paired associates, and comprehensive functional status evaluated by questionnaires, including frailty, social status, and well-being. The effect of the intervention will be examined using a mixed linear model. As a secondary aim, we will test whether the intervention effects vary with the covariates at baseline to examine the effective target attributes.
RESULTS: Recruitment was completed in July 2023. A total of 66 participants were randomly allocated to intervention or control groups. As of January 1, 2024, the intervention is ongoing. Participants are expected to complete the intervention at the end of February 2024, and the postintervention evaluation will be conducted in March 2024.
CONCLUSIONS: This protocol outlines the randomized controlled trial study design evaluating the effect of a 6-month intervention with PICMOA-2. This study will provide evidence on the effectiveness of social interventions on cognitive function and identify effective target images for remote social intervention.
BACKGROUND: UMIN Clinical Trials UMIN000050877; https://tinyurl.com/5eahsy66.
UNASSIGNED: DERR1-10.2196/56608.
OBJECTIVE: This study will examine the effects of \"Photo-Integrated Conversation Moderated by Application version 2\" (PICMOA-2), which is a web-based conversational intervention, on cognitive performance, frailty, and social and psychological indicators among community-dwelling older adults.
METHODS: This study is a randomized controlled trial with an open-label, 2-parallel group trial and 1:1 allocation design. Community dwellers aged 65 years and older were enrolled in the trial and divided into the intervention and control groups. The intervention group receives the PICMOA-2 program, a web-based group conversation, once every 2 weeks for 6 months. The primary outcome is verbal fluency, including phonemic and semantic fluency. The secondary outcomes are other neuropsychiatric batteries, including the Mini-Mental State Examination, Logical Memory (immediate and delay), verbal paired associates, and comprehensive functional status evaluated by questionnaires, including frailty, social status, and well-being. The effect of the intervention will be examined using a mixed linear model. As a secondary aim, we will test whether the intervention effects vary with the covariates at baseline to examine the effective target attributes.
RESULTS: Recruitment was completed in July 2023. A total of 66 participants were randomly allocated to intervention or control groups. As of January 1, 2024, the intervention is ongoing. Participants are expected to complete the intervention at the end of February 2024, and the postintervention evaluation will be conducted in March 2024.
CONCLUSIONS: This protocol outlines the randomized controlled trial study design evaluating the effect of a 6-month intervention with PICMOA-2. This study will provide evidence on the effectiveness of social interventions on cognitive function and identify effective target images for remote social intervention.
BACKGROUND: UMIN Clinical Trials UMIN000050877; https://tinyurl.com/5eahsy66.
UNASSIGNED: DERR1-10.2196/56608.
摘要：
背景：社会交往是维持认知功能的关键因素，并有助于以后的生活幸福。
目的：本研究将检查“应用版本2调节的照片集成对话”（PICMOA-2）的效果，这是一种基于网络的对话干预，关于认知表现，脆弱,以及社区居住老年人的社会和心理指标。
方法：本研究是一项随机对照试验，2-平行组试验和1:1分配设计。65岁及以上的社区居民被纳入试验，并分为干预组和对照组。干预组接受PICMOA-2计划，基于网络的群聊,每2周一次，持续6个月。主要结果是言语流利，包括音素和语义流畅性。次要结果是其他神经精神电池，包括迷你精神状态检查，逻辑内存（即时和延迟），口头配对的同事，以及通过问卷调查评估的综合功能状态，包括脆弱,社会地位,和幸福。将使用混合线性模型检查干预的效果。作为次要目标，我们将在基线时测试干预效果是否随协变量而变化,以检查有效的目标属性.
结果：招募工作于2023年7月完成。共有66名参与者被随机分配到干预组或对照组。截至2024年1月1日，干预正在进行中。预计参与者将在2024年2月底完成干预，干预后评估将在2024年3月进行。
结论：本方案概述了评价PICMOA-26个月干预效果的随机对照试验研究设计。本研究将为社会干预对认知功能的有效性提供证据，并为远程社会干预确定有效的目标图像。
背景：UMIN临床试验UMIN000050877;https://tinyurl.com/5eahsy66.
■DERR1-10.2196/56608。
目的：本研究将检查“应用版本2调节的照片集成对话”（PICMOA-2）的效果，这是一种基于网络的对话干预，关于认知表现，脆弱,以及社区居住老年人的社会和心理指标。
方法：本研究是一项随机对照试验，2-平行组试验和1:1分配设计。65岁及以上的社区居民被纳入试验，并分为干预组和对照组。干预组接受PICMOA-2计划，基于网络的群聊,每2周一次，持续6个月。主要结果是言语流利，包括音素和语义流畅性。次要结果是其他神经精神电池，包括迷你精神状态检查，逻辑内存（即时和延迟），口头配对的同事，以及通过问卷调查评估的综合功能状态，包括脆弱,社会地位,和幸福。将使用混合线性模型检查干预的效果。作为次要目标，我们将在基线时测试干预效果是否随协变量而变化,以检查有效的目标属性.
结果：招募工作于2023年7月完成。共有66名参与者被随机分配到干预组或对照组。截至2024年1月1日，干预正在进行中。预计参与者将在2024年2月底完成干预，干预后评估将在2024年3月进行。
结论：本方案概述了评价PICMOA-26个月干预效果的随机对照试验研究设计。本研究将为社会干预对认知功能的有效性提供证据，并为远程社会干预确定有效的目标图像。
背景：UMIN临床试验UMIN000050877;https://tinyurl.com/5eahsy66.
■DERR1-10.2196/56608。
