Mesh : Humans Vitamin B 12 Deficiency / complications diagnosis Addison Disease / diagnosis etiology complications Hyperpigmentation / etiology diagnosis Male Female Adult Vitamin B 12 Middle Aged

来  源:   DOI:10.59556/japi.72.0570

Abstract:
We report a case series of two patients who had similar skin pigmentation but were caused by vitamin B12 deficiency and Addison\'s disease. We further discuss the pathophysiology of skin hyperpigmentation in both of these disorders and the response to treatment. Our case report highlights the importance of the identification of simple bedside clinical signs to diagnose reversible causes of skin pigmentation.
摘要:
我们报告了一个病例系列,其中两名患者具有相似的皮肤色素沉着,但由维生素B12缺乏和Addison病引起。我们进一步讨论了这两种疾病中皮肤色素沉着过度的病理生理学以及对治疗的反应。我们的病例报告强调了识别简单床旁临床体征以诊断皮肤色素沉着的可逆原因的重要性。
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