METHODS: An observational cross-sectional study was carried out on 85 patients admitted to a referral hospital. The AP patients were categorized into two groups: those with mild AP (MAP) and those with moderately severe/severe AP (MSAP/SAP). RDW was assessed in all patients upon admission and at the 24-hour mark.
RESULTS: Among the 85 AP patients, 55 were diagnosed with MAP, while 17 had MSAP and 13 had SAP. The mean serum calcium levels were notably lower in patients with MSAP/SAP compared to MAP. Additionally, the modified Marshall (MM) score, bedside index for severity in acute pancreatitis (BISAP) index, RDW at 0 hours and 24 hours, and RDW/total serum calcium (RDW/TSC) ratio were significantly higher in patients with MSAP/SAP than in MAP. The BISAP index, followed by MM, emerged as the most reliable predictors of severity, with RDW/TSC also showing strong predictive value. RDW/TSC demonstrated superior predictive ability for AP severity when compared to RDW measured at admission and at 24 hours. However, no individual parameter was identified as an independent significant predictor of AP.
CONCLUSIONS: Red cell distribution width and RDW/TSC ratio are comparable to BISAP index as predictors of severity in AP. They offer a cost-effective and readily accessible means to forecast AP severity upon admission, facilitating prompt intervention at the outset.
方法:对转诊医院收治的85名患者进行了一项观察性横断面研究。AP患者分为两组:轻度AP(MAP)和中度/重度AP(MSAP/SAP)。在所有患者入院时和24小时时评估RDW。
结果:在85例AP患者中,55人被诊断为MAP,17人患有MSAP,13人患有SAP。与MAP相比,MSAP/SAP患者的平均血清钙水平明显较低。此外,修改后的马歇尔(MM)得分,急性胰腺炎严重程度的床旁指数(BISAP)指数,RDW在0小时和24小时,MSAP/SAP患者的RDW/血清总钙(RDW/TSC)比值明显高于MAP。BISAP指数,其次是MM,成为最可靠的严重程度预测因子,RDW/TSC也显示出较强的预测价值。与入院时和24小时测量的RDW相比,RDW/TSC对AP严重程度的预测能力更高。然而,没有个体参数被确定为AP的独立显著预测因子.
结论:红细胞分布宽度和RDW/TSC比率与BISAP指数相当,可以预测AP的严重程度。他们提供了一种具有成本效益且易于获得的方法来预测入院时的AP严重程度,一开始就促进及时干预。