Abstract:
This review provides a thorough examination of small molecule-based fluorescence chemosensors tailored for bioimaging applications, showcasing their unique ability to visualize biological processes with exceptional sensitivity and selectivity. It explores recent advancements, methodologies, and applications in this domain, focusing on various designs rooted in anthracene, benzothiazole, naphthalene, quinoline, and Schiff base. Structural modifications and molecular engineering strategies are emphasized for enhancing sensor performance, including heightened sensitivity, selectivity, and biocompatibility. Additionally, the review offers valuable insights into the ongoing development and utilization of these chemosensors, addressing current challenges and charting future directions in this rapidly evolving field.
摘要:
这篇综述提供了为生物成像应用量身定制的基于小分子的荧光化学传感器的全面检查,展示其独特的可视化生物过程的能力与卓越的灵敏度和选择性。它探讨了最近的进步,方法论,以及该领域的应用程序,专注于植根于蒽的各种设计,苯并噻唑,萘,喹啉,希夫基地。强调结构修饰和分子工程策略以增强传感器性能,包括提高灵敏度,选择性,和生物相容性。此外,该评论为这些化学传感器的持续开发和利用提供了宝贵的见解,解决当前的挑战,并在这个快速发展的领域规划未来的方向。