PDF(Pubmed)
Abstract：
BACKGROUND: Healthcare professionals play an essential role in reporting adverse drug reactions as part of pharmacovigilance activities. However, adverse drug reactions reported by healthcare professionals remain low.
OBJECTIVE: The aim of this systematic review was to investigate healthcare professionals\' knowledge, awareness, attitude, and practice on pharmacovigilance and adverse drug reaction reporting, explore the causes of the underreporting issue, and provide improvement strategies.
METHODS: This systematic review was conducted using four electronic databases for original papers, including PubMed, Scopus, Google Scholar, and Scholar ID. Recent publications from 1st January 2012 to 31st December 2022 were selected. The following terms were used in the search: \"awareness\", \"knowledge\", \"adverse drug reaction\", \"pharmacovigilance\", \"healthcare professional\", and \"underreporting factor\". Articles were chosen, extracted, and reviewed by the two authors.
RESULTS: Twenty-five studies were selected for systematic review. This review found that 24.8%-73.33% of healthcare professionals were unaware of the National Pharmacovigilance Center. Around 20%-95.7% of healthcare professionals have a positive attitude toward pharmacovigilance and adverse drug reaction reporting, while 12%-60.8% of healthcare professionals have experience reporting any adverse drug reaction in their practice. The most frequently highlighted barriers to pharmacovigilance were a lack of awareness and knowledge regarding what, when, and to whom to report.
CONCLUSIONS: Underreporting issues require immediate attention among healthcare professionals due to a lack of awareness and knowledge of pharmacovigilance and adverse drug reaction reporting. Educational and training program interventions have been suggested by most studies to address these issues.
OBJECTIVE: The aim of this systematic review was to investigate healthcare professionals\' knowledge, awareness, attitude, and practice on pharmacovigilance and adverse drug reaction reporting, explore the causes of the underreporting issue, and provide improvement strategies.
METHODS: This systematic review was conducted using four electronic databases for original papers, including PubMed, Scopus, Google Scholar, and Scholar ID. Recent publications from 1st January 2012 to 31st December 2022 were selected. The following terms were used in the search: \"awareness\", \"knowledge\", \"adverse drug reaction\", \"pharmacovigilance\", \"healthcare professional\", and \"underreporting factor\". Articles were chosen, extracted, and reviewed by the two authors.
RESULTS: Twenty-five studies were selected for systematic review. This review found that 24.8%-73.33% of healthcare professionals were unaware of the National Pharmacovigilance Center. Around 20%-95.7% of healthcare professionals have a positive attitude toward pharmacovigilance and adverse drug reaction reporting, while 12%-60.8% of healthcare professionals have experience reporting any adverse drug reaction in their practice. The most frequently highlighted barriers to pharmacovigilance were a lack of awareness and knowledge regarding what, when, and to whom to report.
CONCLUSIONS: Underreporting issues require immediate attention among healthcare professionals due to a lack of awareness and knowledge of pharmacovigilance and adverse drug reaction reporting. Educational and training program interventions have been suggested by most studies to address these issues.
摘要：
背景：作为药物警戒活动的一部分，医疗保健专业人员在报告药物不良反应中起着至关重要的作用。然而,医疗保健专业人员报告的药物不良反应仍然很低。
目的：本系统评价的目的是调查医疗保健专业人员的知识，意识,态度,药物警戒和药物不良反应报告的实践，探索漏报问题的原因，并提供改进策略。
方法：本系统综述使用四个电子数据库进行原始论文，包括PubMed,Scopus,谷歌学者，学者ID。选择了2012年1月1日至2022年12月31日的最新出版物。搜索中使用了以下术语：“意识”，\"知识\",“药物不良反应”，“药物警戒”，“医疗保健专业人员”，和“漏报因素”。文章被选中，提取,并由两位作者审查。
结果：选择了25项研究进行系统评价。这篇综述发现，24.8%-73.33%的医疗保健专业人员不知道国家药物警戒中心。大约20%-95.7%的医疗保健专业人员对药物警戒和药物不良反应报告持积极态度。12％-60.8％的医疗保健专业人员在其实践中有报告任何药物不良反应的经验。最常见的药物警戒障碍是缺乏对什么的认识和知识，when,向谁报告。
结论：由于缺乏药物警戒和药物不良反应报告的认识和知识，因此需要医疗保健专业人员立即关注漏报问题。大多数研究都建议采取教育和培训计划干预措施来解决这些问题。
目的：本系统评价的目的是调查医疗保健专业人员的知识，意识,态度,药物警戒和药物不良反应报告的实践，探索漏报问题的原因，并提供改进策略。
方法：本系统综述使用四个电子数据库进行原始论文，包括PubMed,Scopus,谷歌学者，学者ID。选择了2012年1月1日至2022年12月31日的最新出版物。搜索中使用了以下术语：“意识”，\"知识\",“药物不良反应”，“药物警戒”，“医疗保健专业人员”，和“漏报因素”。文章被选中，提取,并由两位作者审查。
结果：选择了25项研究进行系统评价。这篇综述发现，24.8%-73.33%的医疗保健专业人员不知道国家药物警戒中心。大约20%-95.7%的医疗保健专业人员对药物警戒和药物不良反应报告持积极态度。12％-60.8％的医疗保健专业人员在其实践中有报告任何药物不良反应的经验。最常见的药物警戒障碍是缺乏对什么的认识和知识，when,向谁报告。
结论：由于缺乏药物警戒和药物不良反应报告的认识和知识，因此需要医疗保健专业人员立即关注漏报问题。大多数研究都建议采取教育和培训计划干预措施来解决这些问题。
