PDF(Pubmed)
Abstract：
UNASSIGNED: There have been cases of colorectal cancer (CRC) metastasizing into the ovary. This study reports a case involving solitary ovarian metastasis (OM) from CRC, which is very rare in the absence of other pelvic and peritoneal metastases. This atypical clinical presentation added to the complexity of the diagnosis.
UNASSIGNED: We report a case of solitary OM-CRC in a 48-year-old woman. The patient underwent CRC surgery and refused follow-up after three rounds of chemotherapy. Approximately 14 months later, the patient presented with vaginal bleeding for 2 months. The magnetic resonance imaging (MRI) showed a huge solid cystic mass in the right adnexa. Intraoperatively, the right ovary was found to be enlarged and smooth without adhesions. By careful examination of the abdominal cavity, no metastatic lesions were found in the left ovary and uterus, and no seedings were found in the rest of the pelvis and abdomen. After removal of the uterus and bilateral adnexa, the histologic examination revealed metastatic adenocarcinoma of the right ovary with a considered rectal carcinoma of origin. Positive staining for multiple tumor-associated markers, which further established the primary nature of CRC. These findings support a possible diagnosis of primary CRC and ovarian metastases. The patient recovered well after the operation and no recurrence or metastasis was seen 18 months after the operation.
UNASSIGNED: Solitary ovarian metastases from CRC can be better managed and treated by increasing clinicians\' vigilance for this rare condition. This helps to improve the patient\'s prognosis and quality of life.
UNASSIGNED: We report a case of solitary OM-CRC in a 48-year-old woman. The patient underwent CRC surgery and refused follow-up after three rounds of chemotherapy. Approximately 14 months later, the patient presented with vaginal bleeding for 2 months. The magnetic resonance imaging (MRI) showed a huge solid cystic mass in the right adnexa. Intraoperatively, the right ovary was found to be enlarged and smooth without adhesions. By careful examination of the abdominal cavity, no metastatic lesions were found in the left ovary and uterus, and no seedings were found in the rest of the pelvis and abdomen. After removal of the uterus and bilateral adnexa, the histologic examination revealed metastatic adenocarcinoma of the right ovary with a considered rectal carcinoma of origin. Positive staining for multiple tumor-associated markers, which further established the primary nature of CRC. These findings support a possible diagnosis of primary CRC and ovarian metastases. The patient recovered well after the operation and no recurrence or metastasis was seen 18 months after the operation.
UNASSIGNED: Solitary ovarian metastases from CRC can be better managed and treated by increasing clinicians\' vigilance for this rare condition. This helps to improve the patient\'s prognosis and quality of life.
摘要：
■已经有结肠直肠癌（CRC）转移到卵巢的病例。这项研究报告了一例涉及CRC的孤立性卵巢转移（OM）的病例，在没有其他盆腔和腹膜转移的情况下非常罕见。这种非典型的临床表现增加了诊断的复杂性。
■我们报告了一名48岁女性的单发OM-CRC病例。患者接受了CRC手术，并在三轮化疗后拒绝随访。大约14个月后,患者出现阴道出血2个月。磁共振成像（MRI）显示右侧附件中有一个巨大的实性囊性肿块。术中,发现右卵巢增大且光滑，无粘连。通过仔细检查腹腔，左侧卵巢和子宫未发现转移灶,在骨盆和腹部的其余部分没有发现种子。切除子宫和双侧附件后，组织学检查显示，右侧卵巢转移性腺癌，被认为是起源的直肠癌。多种肿瘤相关标志物阳性染色，这进一步确立了CRC的首要性质。这些发现支持原发性CRC和卵巢转移的可能诊断。患者术后恢复良好，术后18个月无复发或转移。
■通过提高临床医生对这种罕见疾病的警惕性，可以更好地管理和治疗来自CRC的孤立性卵巢转移。这有助于改善患者的预后和生活质量。
■我们报告了一名48岁女性的单发OM-CRC病例。患者接受了CRC手术，并在三轮化疗后拒绝随访。大约14个月后,患者出现阴道出血2个月。磁共振成像（MRI）显示右侧附件中有一个巨大的实性囊性肿块。术中,发现右卵巢增大且光滑，无粘连。通过仔细检查腹腔，左侧卵巢和子宫未发现转移灶,在骨盆和腹部的其余部分没有发现种子。切除子宫和双侧附件后，组织学检查显示，右侧卵巢转移性腺癌，被认为是起源的直肠癌。多种肿瘤相关标志物阳性染色，这进一步确立了CRC的首要性质。这些发现支持原发性CRC和卵巢转移的可能诊断。患者术后恢复良好，术后18个月无复发或转移。
■通过提高临床医生对这种罕见疾病的警惕性，可以更好地管理和治疗来自CRC的孤立性卵巢转移。这有助于改善患者的预后和生活质量。
