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Abstract：
BACKGROUND: Depression significantly impacts the quality of life and medical care in patients with coronary heart disease (CHD). This study assesses the burden of depression in adults aged 40 years and above with CHD and evaluates predictors of depression in this population. It has been reported that approximately 17-44% of persons with CHD have a major depression diagnosis and that nearly 27% of individuals undergoing coronary artery bypass graft operation suffer depression following the procedure. Methods: Data from the 2022 National Health Interview Survey was used. The sample was made up of adults 40 years and above with CHD. A chi-square analysis was used to identify differences between those who were depressed and those who were not. Logistic and ordinal regression analyses were used to identify predictors of depression and severe depression, respectively.
RESULTS: The proportion of adults 40 years and above with CHD who reported having depression was 863/1700 (50.5%). Among those who were ≥65, the proportion of those who reported depression and those who did not were similar (49.3% vs. 50.7%). Most women reported having depression (57.4% vs. 42.6%), while fewer men reported having depression (46.3% vs. 53.7%). The positive predictors of depression include being insured (odds ratio (OR) 1.26 (1.05-1.53), p = 0.016), college degree (OR 1.09 (1.01-1.18), p = 0.040), diabetes mellitus (OR 1.28 (1.15-1.42), p < 0.001), and hypertension (OR 1.34 (1.24-1.44), p < 0.001). The negative predictors of being depressed were age ≥65 (OR 0.74 (0.69-0.80), p < 0.001), male sex (OR 0.54 (0.50-0.58), p < 0.001), and ratio of family income (RFI) ≥1 (OR 0.68 (0.61-0.77), p < 0.001). The positive predictors of severe depression include diabetes mellitus (OR 1.38 (1.06-1.81), p = 0.019) and current cigarette use (OR 2.10 (1.44-3.07), p < 0.001).
CONCLUSIONS: A significant proportion of adults 40 years and above with CHD have depression, and socioeconomic and cardiovascular risk factors are associated with a high likelihood of depression. Cardiovascular risk factors alone predict the likelihood of severe depression. Interventions to address depression in CHD should target specifically these high-risk individuals.
RESULTS: The proportion of adults 40 years and above with CHD who reported having depression was 863/1700 (50.5%). Among those who were ≥65, the proportion of those who reported depression and those who did not were similar (49.3% vs. 50.7%). Most women reported having depression (57.4% vs. 42.6%), while fewer men reported having depression (46.3% vs. 53.7%). The positive predictors of depression include being insured (odds ratio (OR) 1.26 (1.05-1.53), p = 0.016), college degree (OR 1.09 (1.01-1.18), p = 0.040), diabetes mellitus (OR 1.28 (1.15-1.42), p < 0.001), and hypertension (OR 1.34 (1.24-1.44), p < 0.001). The negative predictors of being depressed were age ≥65 (OR 0.74 (0.69-0.80), p < 0.001), male sex (OR 0.54 (0.50-0.58), p < 0.001), and ratio of family income (RFI) ≥1 (OR 0.68 (0.61-0.77), p < 0.001). The positive predictors of severe depression include diabetes mellitus (OR 1.38 (1.06-1.81), p = 0.019) and current cigarette use (OR 2.10 (1.44-3.07), p < 0.001).
CONCLUSIONS: A significant proportion of adults 40 years and above with CHD have depression, and socioeconomic and cardiovascular risk factors are associated with a high likelihood of depression. Cardiovascular risk factors alone predict the likelihood of severe depression. Interventions to address depression in CHD should target specifically these high-risk individuals.
摘要：
背景：抑郁症显著影响冠心病患者的生活质量和医疗护理。这项研究评估了40岁及以上冠心病患者的抑郁负担，并评估了该人群中抑郁的预测因素。据报道，大约17-44％的CHD患者被诊断患有严重的抑郁症，并且近27％的接受冠状动脉旁路移植手术的个体在手术后患有抑郁症。方法：使用2022年全国健康访谈调查数据。样本由40岁及以上患有冠心病的成年人组成。卡方分析用于确定抑郁症患者与抑郁症患者之间的差异。Logistic和序数回归分析用于确定抑郁症和重度抑郁症的预测因子。分别。
结果：40岁及以上的冠心病患者报告患有抑郁症的比例为863/1700（50.5%）。在≥65岁的人群中，报告抑郁症和未报告抑郁症的比例相似(49.3%vs.50.7%）。大多数女性报告患有抑郁症(57.4%vs.42.6%），而较少的男性报告患有抑郁症(46.3%vs.53.7%）。抑郁症的积极预测因素包括被保险(赔率比(OR)1.26(1.05-1.53)，p=0.016),大学学位（OR1.09（1.01-1.18），p=0.040),糖尿病（OR1.28（1.15-1.42），p<0.001)，和高血压（OR1.34（1.24-1.44），p<0.001)。抑郁的阴性预测因素是年龄≥65(OR0.74(0.69-0.80)，p<0.001)，男性（OR0.54（0.50-0.58），p<0.001)，家庭收入比率（RFI）≥1（OR0.68（0.61-0.77），p<0.001)。严重抑郁症的阳性预测因子包括糖尿病（OR1.38（1.06-1.81），p=0.019)和当前香烟使用(OR2.10(1.44-3.07)，p<0.001)。
结论：40岁及以上的冠心病成年人中有很大一部分患有抑郁症，社会经济和心血管危险因素与抑郁症的可能性很高。心血管危险因素单独预测严重抑郁症的可能性。应对冠心病抑郁症的干预措施应特别针对这些高危人群。
结果：40岁及以上的冠心病患者报告患有抑郁症的比例为863/1700（50.5%）。在≥65岁的人群中，报告抑郁症和未报告抑郁症的比例相似(49.3%vs.50.7%）。大多数女性报告患有抑郁症(57.4%vs.42.6%），而较少的男性报告患有抑郁症(46.3%vs.53.7%）。抑郁症的积极预测因素包括被保险(赔率比(OR)1.26(1.05-1.53)，p=0.016),大学学位（OR1.09（1.01-1.18），p=0.040),糖尿病（OR1.28（1.15-1.42），p<0.001)，和高血压（OR1.34（1.24-1.44），p<0.001)。抑郁的阴性预测因素是年龄≥65(OR0.74(0.69-0.80)，p<0.001)，男性（OR0.54（0.50-0.58），p<0.001)，家庭收入比率（RFI）≥1（OR0.68（0.61-0.77），p<0.001)。严重抑郁症的阳性预测因子包括糖尿病（OR1.38（1.06-1.81），p=0.019)和当前香烟使用(OR2.10(1.44-3.07)，p<0.001)。
结论：40岁及以上的冠心病成年人中有很大一部分患有抑郁症，社会经济和心血管危险因素与抑郁症的可能性很高。心血管危险因素单独预测严重抑郁症的可能性。应对冠心病抑郁症的干预措施应特别针对这些高危人群。
