Abstract:
Tuberculosis (TB) is one of the leading infectious causes of morbidity and mortality worldwide. Either in its pulmonary (PTB) or extrapulmonary forms (EPTB), TB has a wide variety of manifestations, including hematological ones like thrombocytosis (especially in PTB) and thrombocytopenia (mainly with disseminated or miliary TB). Hematological manifestations are infrequently presenting features of TB, and within them, immune thrombocytopenic purpura (ITP)-associated TB is one of the rarest presenting features. We report a case of a 22-year-old woman with a diagnosis of ganglionic tuberculosis (GTB) presenting with ITP. The therapeutic approach was challenging and included the use, originally, of intravenous immunoglobulin 30 mg/day for five days and, posteriorly, of high-dose corticosteroids (dexamethasone 40 mg/day) and anti-tubercular therapy with satisfactory outcomes.
摘要:
结核病(TB)是世界范围内发病率和死亡率的主要传染性原因之一。无论是肺型(PTB)还是肺外型(EPTB),结核病有各种各样的表现,包括血液学的,如血小板增多症(尤其是PTB)和血小板减少症(主要伴有播散性或粒性TB)。血液学表现很少表现出TB的特征,在其中,免疫性血小板减少性紫癜(ITP)相关的结核病是最罕见的表现特征之一。我们报告了一例22岁的女性,诊断为神经节结核(GTB)并伴有ITP。治疗方法具有挑战性,包括使用,最初,静脉注射免疫球蛋白30毫克/天,持续五天,后面,大剂量皮质类固醇(地塞米松40mg/天)和抗结核治疗,结果令人满意。