PDF(Pubmed)
Abstract：
Although patients believe that osteoporosis is a painful condition, health professionals assume it is painless unless a fracture occurs. The association between BMD and back pain has not been examined longitudinally in community-based adults in an unbiased population using gold-standard measures. This study aimed to examine the association between BMD and incident high-intensity back pain and/or high disability over 10 years in Australian men without high-intensity symptoms at baseline. Men with no high-intensity back pain and/or high disability attending the Geelong Osteoporosis Study at the 5-year visit (occurring between 2006-2010) (considered the baseline for the current study) were followed for 10 years (reassessed between 2016-2021). Back pain and disability were assessed using the Graded Chronic Pain Scale at both time points. At baseline, DXA was used to measure lumbar spine and total hip BMD and spinal artefacts. The relationships between BMD and incident high-intensity pain and/or high disability at follow-up were examined using binary logistic regression, adjusted for age, body mass index, depression, education, smoking, mobility, and spinal artefacts. A total of 679 participants had no to low-intensity pain and/or no to low disability at baseline. A total of 441 attended follow-up, providing back pain and disability data. Thirty-seven men developed high-intensity pain and/or high disability. No association of BMD at any site was seen with incident high-intensity pain and/or high disability. BMD was not associated with incident high-intensity pain or disability in community-based men. These data provide evidence to dispel the erroneous community-held belief that low BMD is related to back pain and disability.
摘要：
尽管患者认为骨质疏松症是一种痛苦的疾病，卫生专业人员认为它是无痛的，除非发生骨折。尚未使用金标准措施在无偏见人群中对社区成年人的BMD与背痛之间的关联进行纵向检查。这项研究旨在研究在基线时没有高强度症状的澳大利亚男性中，BMD与高强度背痛和/或高残疾之间的关系。在5年的访视（2006-2010年之间发生）（被认为是本研究的基线）中参加吉朗骨质疏松症研究的无高强度背痛和/或高残疾的男性随访10年（2016-2021年之间重新评估）。在两个时间点使用慢性疼痛分级量表评估背痛和残疾。在基线,DXA用于测量腰椎和全髋关节BMD和脊柱伪影。使用二元逻辑回归检查BMD与随访时发生的高强度疼痛和/或高残疾之间的关系，根据年龄调整，身体质量指数,抑郁症,教育,吸烟,移动性,和脊髓伪影。共有679名参与者在基线时没有低强度疼痛和/或没有低残疾。共有441人参加了随访，提供背痛和残疾数据。37名男性出现了高强度疼痛和/或高残疾。在任何部位均未发现BMD与高强度疼痛和/或高残疾相关。BMD与社区男性的高强度疼痛或残疾无关。这些数据提供了证据，以消除社区认为低BMD与背痛和残疾有关的错误信念。
