PDF(Pubmed)
Abstract：
UNASSIGNED: Hyaluronic acid (HA) fillers, popular for facial cosmetic enhancements, pose risks of vascular complications like skin necrosis due to arterial blockage, necessitating effective treatments such as hyperbaric oxygen therapy (HBOT).
UNASSIGNED: This study presents a series of cases where measurements of transcutaneous oxygen pressure (TcPO2) informed the application of HBOT for skin necrosis induced by HA.
UNASSIGNED: In cases 1 and 3, following the injection of HA, potential skin necrosis was observed. In addition to standard treatment, TcPO2 revealed values below 40 mmHg, indicating tissue hypoxia. Treatment with HBOT increased TcPO2 levels to above 200 mmHg, suggesting that HBOT could correct the hypoxia. Monitoring TcPO2 levels also aided in determining the optimal time to discontinue HBOT. In cases 2 and 4, patients received standard treatment, resulting in TcPO2 levels above 40 mmHg, indicating adequate tissue oxygenation, and no additional HBOT was administered. All four patients mentioned above showed good clinical recovery.
UNASSIGNED: This study investigates the application of TcPO2 measurement technology in aiding decisions on whether to utilize HBOT in the treatment of complications arising from HA fillers, as well as in optimizing HBOT protocols.
UNASSIGNED: This study presents a series of cases where measurements of transcutaneous oxygen pressure (TcPO2) informed the application of HBOT for skin necrosis induced by HA.
UNASSIGNED: In cases 1 and 3, following the injection of HA, potential skin necrosis was observed. In addition to standard treatment, TcPO2 revealed values below 40 mmHg, indicating tissue hypoxia. Treatment with HBOT increased TcPO2 levels to above 200 mmHg, suggesting that HBOT could correct the hypoxia. Monitoring TcPO2 levels also aided in determining the optimal time to discontinue HBOT. In cases 2 and 4, patients received standard treatment, resulting in TcPO2 levels above 40 mmHg, indicating adequate tissue oxygenation, and no additional HBOT was administered. All four patients mentioned above showed good clinical recovery.
UNASSIGNED: This study investigates the application of TcPO2 measurement technology in aiding decisions on whether to utilize HBOT in the treatment of complications arising from HA fillers, as well as in optimizing HBOT protocols.
摘要：
■透明质酸（HA）填料，流行的面部美容增强，构成血管并发症的风险，如由于动脉阻塞引起的皮肤坏死，需要有效的治疗，如高压氧治疗（HBOT）。
■本研究提出了一系列情况，其中经皮氧分压（TcPO2）的测量为HBOT用于HA引起的皮肤坏死的应用提供了依据。
■在情况1和3中，在注入HA之后，观察到潜在的皮肤坏死。除了标准治疗，TcPO2显示值低于40mmHg，表明组织缺氧。用HBOT治疗可将TcPO2水平提高到200mmHg以上，表明HBOT可以纠正缺氧。监测TcPO2水平还有助于确定中断HBOT的最佳时间。在病例2和4中，患者接受了标准治疗，导致TcPO2水平高于40mmHg，表明足够的组织氧合，并且没有给予额外的HBOT。上述4例患者均表现出良好的临床恢复。
■本研究调查了TcPO2测量技术在帮助决定是否利用HBOT治疗HA填充物引起的并发症中的应用，以及优化HBOT协议。
■本研究提出了一系列情况，其中经皮氧分压（TcPO2）的测量为HBOT用于HA引起的皮肤坏死的应用提供了依据。
■在情况1和3中，在注入HA之后，观察到潜在的皮肤坏死。除了标准治疗，TcPO2显示值低于40mmHg，表明组织缺氧。用HBOT治疗可将TcPO2水平提高到200mmHg以上，表明HBOT可以纠正缺氧。监测TcPO2水平还有助于确定中断HBOT的最佳时间。在病例2和4中，患者接受了标准治疗，导致TcPO2水平高于40mmHg，表明足够的组织氧合，并且没有给予额外的HBOT。上述4例患者均表现出良好的临床恢复。
■本研究调查了TcPO2测量技术在帮助决定是否利用HBOT治疗HA填充物引起的并发症中的应用，以及优化HBOT协议。
