PDF(Pubmed)
Abstract：
This review provides a comprehensive overview of the therapeutic and diagnostic implications of fluorescence imaging in neurosurgery. Fluorescence imaging has become a valuable intraoperative visualization and guidance tool, facilitating precise surgical interventions. The therapeutic role of fluorescence is examined, including its application in photodynamic therapy and tumor-targeted therapy. It also explores its diagnostic capabilities in tumor detection, margin assessment, and blood-brain barrier evaluation. Drawing from clinical and preclinical studies, the review underscores the growing evidence supporting the efficacy of fluorescence imaging in neurosurgical practice. Furthermore, it discusses current limitations and future directions, emphasizing the potential for emerging technologies to enhance the utility and accessibility of fluorescence imaging, ultimately improving patient outcomes in neurosurgery.
摘要：
这篇综述全面概述了神经外科荧光成像的治疗和诊断意义。荧光成像已成为一种有价值的术中可视化和指导工具，促进精确的手术干预。检查了荧光的治疗作用，包括其在光动力治疗和肿瘤靶向治疗中的应用。它还探索了其在肿瘤检测中的诊断能力，保证金评估，和血脑屏障评估。根据临床和临床前研究，这篇综述强调了越来越多的证据支持荧光成像在神经外科实践中的有效性.此外，它讨论了当前的局限性和未来的方向，强调新兴技术增强荧光成像的实用性和可及性的潜力，最终改善神经外科患者的预后。
