PDF(Pubmed)
Abstract：
Congenital syphilis (CS) is a vertically transmitted infection caused by the spirochete Treponema pallidum. It is seen rarely due to proper antenatal screening. Signs and symptoms appear within the first 2 years of life in early CS and after 2 years in late CS. Failure to diagnose and treat CS in its early stages can result in higher morbidity and mortality. Skin manifestations can guide toward the diagnosis of CS at an early stage. Here, we report a 2-day-old neonate who presented with acral peeling of skin along with respiratory distress and hepatosplenomegaly. Clinical suspicion of CS was made and subsequently confirmed by a positive venereal disease research laboratory test in both mother and child. The child was treated with aqueous crystalline penicillin G as per the CDC guidelines.
摘要：
先天性梅毒（CS）是由梅毒螺旋体引起的垂直传播感染。由于适当的产前筛查，很少见。体征和症状出现在早期CS的生命的前2年和晚期CS的2年后。早期不能诊断和治疗CS会导致更高的发病率和死亡率。皮肤表现可以指导早期CS的诊断。这里,我们报告了一名2天大的新生儿，他出现了肢端皮肤脱落，并伴有呼吸窘迫和肝脾肿大。对CS进行了临床怀疑，随后在母亲和儿童中进行了阳性性病研究实验室检查。根据CDC指南，该儿童接受了水性结晶青霉素G治疗。
