关键词: Schwann cells cellular hierarchy gland development normal neural crest stem cells pluripotency

来  源:   DOI:10.3389/fcell.2024.1406199   PDF(Pubmed)

Abstract:
In this review, we consider the multipotency of neural crest cells (NCCs), Schwann cell precursors (SCPs), and their role in embryogenesis base on genetic tracing and knock out model animals and single cell transcriptomic analysis. In particular, we summarize and analyze data on the contribution of NCCs and SCPs to the gland development and functions.
摘要:
在这次审查中,我们考虑神经c细胞(NCC)的多能性,雪旺氏细胞前体(SCP),基于遗传追踪和敲除模型动物和单细胞转录组学分析,以及它们在胚胎发生中的作用。特别是,我们总结和分析了NCCs和SCP对腺体发育和功能的贡献。
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