PDF(Pubmed)
Abstract：
Bromide is the first effective antiseizure medication used in human medicine since the XIX century. Initially met with skepticism, bromide quickly gained enthusiasm within the medical field until being largely replaced by newer antiseizure medications with significantly fewer adverse effects in people. In veterinary medicine, bromide continues to be used in the management of epileptic patients for over 30 years, yet adverse effects can impact owners and patients alike. We sought to provide the general practitioner and veterinary neurologist with insightful information on both the positive and negative attributes of bromide, explore factors that may influence its desirability as an antiseizure medication in specific veterinary cases and elucidate its current role in modern epilepsy treatment for veterinary patients. It\'s also our endeavor to discuss the current use as an alternative or add-on with other known antiseizure medications and potential future studies that might enhance our understanding and use of this medication.
摘要：
溴化物是自十九世纪以来在人类医学中使用的第一种有效的抗癫痫药物。最初遇到了怀疑，溴化物在医学领域迅速获得了热情，直到被新的抗癫痫药物取代，对人的不良反应明显减少。在兽医学中，30多年来，溴化物继续用于治疗癫痫患者，然而不良反应会影响业主和患者。我们试图为全科医生和兽医神经科医生提供关于溴化物的积极和消极属性的有见地的信息，探索可能影响其在特定兽医病例中作为抗癫痫药物的可取性的因素，并阐明其在兽医患者现代癫痫治疗中的当前作用。这也是我们的努力，讨论目前的使用作为替代或附加与其他已知的抗癫痫药物和潜在的未来研究，可能会提高我们的理解和使用这种药物。
