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Abstract：
UNASSIGNED: Our research aimed to study the microbiology and antimicrobial resistance in asymptomatic bacteriuria (ASB) among Omani pregnant women.
UNASSIGNED: We conducted a retrospective study that included data from 196 Omani pregnant women with ASB who received care at Sultan Qaboos University Hospital from 2010-2019. Data were obtained from the patients\' electronic medical records including demographics, clinical details, isolated organisms, antimicrobial susceptibility results, and prescribed antibiotics.
UNASSIGNED: ASB was detected in 56.1% of cases during the third trimester. Klebsiella pneumoniae(32.1%) was the most frequently isolated organism, followed by Escherichia coli (29.6%). Twenty-one (10.7%) isolates were extended-spectrum beta-lactamase (ESBL)-producing organisms. The overall microbiological susceptibility pattern showed that organisms have a high susceptibility rate to nitrofurantoin reaching 82.8%, followed to a lesser extent by cefuroxime and augmentin. The susceptibility of E. coli and K. pneumoniae to cefuroxime was 74.1% and 71.4%, respectively. Only 52.4% of all isolated ESBL-producing organisms were susceptible to nitrofurantoin.
UNASSIGNED: K. pneumoniae and E. coli were the most frequently isolated bacteria in ASB, representing 60.7% of total isolates. A high prevalence of ESBL-producing organisms, 10.7% of the total isolates, was observed. Cefuroxime is an appropriate empirical antibacterial therapy for ASB and urinary tract infection in pregnant women. Nitrofurantoin should be considered for empirical antibiotic therapy in settings of high prevalence of ESBL-producing organisms.
UNASSIGNED: We conducted a retrospective study that included data from 196 Omani pregnant women with ASB who received care at Sultan Qaboos University Hospital from 2010-2019. Data were obtained from the patients\' electronic medical records including demographics, clinical details, isolated organisms, antimicrobial susceptibility results, and prescribed antibiotics.
UNASSIGNED: ASB was detected in 56.1% of cases during the third trimester. Klebsiella pneumoniae(32.1%) was the most frequently isolated organism, followed by Escherichia coli (29.6%). Twenty-one (10.7%) isolates were extended-spectrum beta-lactamase (ESBL)-producing organisms. The overall microbiological susceptibility pattern showed that organisms have a high susceptibility rate to nitrofurantoin reaching 82.8%, followed to a lesser extent by cefuroxime and augmentin. The susceptibility of E. coli and K. pneumoniae to cefuroxime was 74.1% and 71.4%, respectively. Only 52.4% of all isolated ESBL-producing organisms were susceptible to nitrofurantoin.
UNASSIGNED: K. pneumoniae and E. coli were the most frequently isolated bacteria in ASB, representing 60.7% of total isolates. A high prevalence of ESBL-producing organisms, 10.7% of the total isolates, was observed. Cefuroxime is an appropriate empirical antibacterial therapy for ASB and urinary tract infection in pregnant women. Nitrofurantoin should be considered for empirical antibiotic therapy in settings of high prevalence of ESBL-producing organisms.
摘要：
■我们的研究旨在研究阿曼孕妇无症状性菌尿（ASB）的微生物学和抗菌素耐药性。
■我们进行了一项回顾性研究，其中包括2010-2019年在苏丹卡布斯大学医院接受护理的196名阿曼ASB孕妇的数据。数据来自患者的电子病历，包括人口统计，临床细节，孤立的生物体，抗菌药物敏感性结果，开了抗生素.
■在妊娠晚期的56.1％的病例中检测到ASB。肺炎克雷伯菌(32.1%)是最常见的分离菌,其次是大肠杆菌(29.6%)。21株（10.7％）是产超广谱β-内酰胺酶（ESBL）的生物。总体微生物敏感性表明，生物体对呋喃妥因的敏感性较高，达到82.8%，其次是头孢呋辛和augmentin。大肠埃希菌和肺炎克雷伯菌对头孢呋辛的敏感性分别为74.1%和71.4%,分别。所有分离的产ESBL生物中只有52.4％对呋喃妥因敏感。
■K.肺炎和大肠杆菌是ASB中最常见的细菌，占分离株总数的60.7%。产ESBL生物的患病率很高，占分离株总数的10.7%,被观察到。头孢呋辛是孕妇ASB和尿路感染的适当经验性抗菌疗法。在产生ESBL的生物体患病率较高的情况下，应考虑将呋喃妥因用于经验性抗生素治疗。
■我们进行了一项回顾性研究，其中包括2010-2019年在苏丹卡布斯大学医院接受护理的196名阿曼ASB孕妇的数据。数据来自患者的电子病历，包括人口统计，临床细节，孤立的生物体，抗菌药物敏感性结果，开了抗生素.
■在妊娠晚期的56.1％的病例中检测到ASB。肺炎克雷伯菌(32.1%)是最常见的分离菌,其次是大肠杆菌(29.6%)。21株（10.7％）是产超广谱β-内酰胺酶（ESBL）的生物。总体微生物敏感性表明，生物体对呋喃妥因的敏感性较高，达到82.8%，其次是头孢呋辛和augmentin。大肠埃希菌和肺炎克雷伯菌对头孢呋辛的敏感性分别为74.1%和71.4%,分别。所有分离的产ESBL生物中只有52.4％对呋喃妥因敏感。
■K.肺炎和大肠杆菌是ASB中最常见的细菌，占分离株总数的60.7%。产ESBL生物的患病率很高，占分离株总数的10.7%,被观察到。头孢呋辛是孕妇ASB和尿路感染的适当经验性抗菌疗法。在产生ESBL的生物体患病率较高的情况下，应考虑将呋喃妥因用于经验性抗生素治疗。
