Abstract:
Inflammatory myofibroblastic tumors (IMTs) are mesenchymal tumors of intermediate malignant potential. Gastric IMTs are rare and commonly affect young adults. They are typically confused with gastrointestinal stromal tumors, inflammatory fibroid polyps, and leiomyosarcomas. The etiology of IMTs remains unclear, but is theorized to be due to hyperinflammatory response to chronic infections. We present a middle-aged woman found to have a gastric mass positive for Helicobacter pylori, underwent multiple endoscopies with endoscopic ultrasound, and a definitive diagnosis of gastric IMT was only made after a partial gastrectomy with immunohistochemistry negative for CD-117, S-100, ALK-1, and positive for vimentin and SMA.
摘要:
炎性肌纤维母细胞瘤(IMT)是具有中等恶性潜能的间充质肿瘤。胃IMT很少见,通常会影响年轻人。它们通常与胃肠道间质瘤混淆,炎性纤维息肉,和平滑肌肉瘤.IMT的病因仍不清楚,但理论上是由于对慢性感染的高炎症反应。我们介绍了一名中年妇女,发现胃部幽门螺杆菌呈阳性,接受了内窥镜超声检查,只有在部分胃切除术后才明确诊断胃IMT,CD-117,S-100,ALK-1免疫组织化学阴性,波形蛋白和SMA阳性。