关键词: mild pulmonary vein obstruction reoperation retrospective cohort study risk factor total anomalous pulmonary venous connection

来  源:   DOI:10.3389/fcvm.2024.1399659   PDF(Pubmed)

Abstract:
UNASSIGNED: This study investigates the impact of mild pulmonary vein obstruction, detected via echocardiography before hospital discharge, on the likelihood of reoperation in patients who have undergone repair for Total Anomalous Pulmonary Venous Connection (TAPVC).
UNASSIGNED: Utilizing a single-center, retrospective cohort approach, we analyzed 38 cases from October 2017 to December 2023, excluding patients with functionally univentricular circulations or atrial isomerism. Our primary outcome was the necessity for reoperation within one year due to anatomical issues related to the initial TAPVC repair. Mild obstruction was defined as a pulmonary vein flow velocity ≥1.2 m/s.
UNASSIGNED: Our findings revealed that 31.6% of patients exhibited pre-discharge mild obstruction. During the median follow-up of 10 months, reoperations were notably higher in the mild obstruction group compared to the normal group, with a significant association between pre-discharge mild obstruction and increased risk of reoperation. Specifically, in the fully adjusted model, mild obstruction was linked to a 13.9-fold increased risk of reoperation.
UNASSIGNED: Our results suggest that a pre-discharge echocardiography Doppler velocity threshold of 1.2 m/s could serve as a critical predictor for reoperation, emphasizing the need for targeted follow-up strategies for at-risk patients.
摘要:
这项研究调查了轻度肺静脉阻塞的影响,出院前通过超声心动图检测,对全肺静脉畸形连接(TAPVC)进行修复的患者进行再手术的可能性。
利用单中心,回顾性队列方法,我们分析了2017年10月至2023年12月的38例病例,不包括功能单室循环或心房异构的患者.我们的主要结果是由于与初始TAPVC修复相关的解剖学问题,需要在一年内再次手术。轻度阻塞定义为肺静脉流速≥1.2m/s。
我们的研究结果显示,31.6%的患者出现出院前轻度梗阻。在10个月的中位随访期间,轻度梗阻组的再手术率明显高于正常组,出院前轻度梗阻和再手术风险增加之间存在显著关联。具体来说,在完全调整的模型中,轻度梗阻与再次手术风险增加13.9倍相关.
我们的结果表明,1.2m/s的出院前超声心动图多普勒速度阈值可以作为再次手术的关键预测指标,强调需要针对高危患者采取有针对性的随访策略.
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