Abstract:
This article reviews the latest research on pharmacological management of eating disorders, including anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), and avoidant/restrictive food intake disorder. Recent literature for both youth and adult populations obtained through a PubMed search was included. American Psychiatric Association guidelines, National Institute for Health and Care Excellence guidelines, Canadian practice guidelines, and World Federation of Societies of Biological Psychiatry guidelines were also included. First-line recommendations were focused on therapy because the evidence for medication management of eating disorders continues to be limited. Some limited evidence was found for antipsychotic use for AN, selective serotonin reuptake inhibitors and topiramate use for BN, and stimulant and topiramate use for BED. Further medication trials are needed to help with complex eating disorder presentations in adults and youth.
摘要:
本文综述了饮食失调的药物管理的最新研究,包括神经性厌食症(AN),神经性贪食症(BN),暴饮暴食症(BED),和回避性/限制性食物摄入障碍。包括通过PubMed搜索获得的有关青年和成人的最新文献。美国精神病学协会指南,国家健康与护理卓越研究所指南,加拿大实践指南,和世界生物精神病学协会联合会指南也包括在内。一线建议集中在治疗上,因为饮食失调的药物管理证据仍然有限。一些有限的证据被发现用于抗精神病药,选择性5-羟色胺再摄取抑制剂和托吡酯用于BN,和兴奋剂和托吡酯用于床。需要进一步的药物试验来帮助成年人和年轻人出现复杂的饮食失调。