PDF(Pubmed)
Abstract：
Unlike psychopharmacologic interventions for other psychiatric conditions, few medications have emerged as helpful in improving eating disorder cognitions and evidence-based psychotherapies fail many patients. Novel treatments are urgently needed to address anorexia nervosa (AN), which is increasingly prevalent and difficult to treat. This article provides an overview of preliminary investigations into cannabidiol, psilocybin therapy, ketamine and the ketogenic diet, transcranial magnetic stimulation, and vagus nerve stimulation in individuals with AN. These pilot studies underscore the need for larger clinical trials that include more participant diversity in order to rapidly translate findings to real-world clinical practice.
摘要：
与其他精神疾病的精神药理学干预不同，很少有药物有助于改善饮食失调的认知和循证心理治疗使许多患者失败。迫切需要新的治疗方法来解决神经性厌食症(AN)，越来越普遍和难以治疗。本文概述了大麻二酚的初步研究，psilocybin治疗,氯胺酮和生酮饮食，经颅磁刺激,和迷走神经刺激患有AN的个体。这些试点研究强调了需要更大的临床试验，包括更多参与者的多样性，以便将研究结果快速转化为现实世界的临床实践。
