Abstract：
Liver disorders present a significant global health challenge, necessitating the exploration of innovative treatment modalities. Liposomal nanocarriers have emerged as promising candidates for targeted drug delivery to the liver. This review offers a comprehensive examination of the mechanisms and applications of liposomal nanocarriers in addressing various liver disorders. Firstly discussing the liver disorders and the conventional treatment approaches, the review delves into the liposomal structure and composition. Moreover, it tackles the different mechanisms of liposomal targeting including both passive and active strategies. After that, the review moves on to explore the therapeutic potentials of liposomal nanocarriers in treating liver cirrhosis, fibrosis, viral hepatitis, and hepatocellular carcinoma. Through discussing recent advancements and envisioning future perspectives, this review highlights the role of liposomal nanocarriers in enhancing the effectiveness and the safety of liver disorders and consequently improving patient outcomes and enhances life quality.
摘要：
肝脏疾病提出了重大的全球健康挑战，有必要探索创新的治疗方式。脂质体纳米载体已经成为靶向药物递送至肝脏的有希望的候选物。这篇综述提供了脂质体纳米载体在解决各种肝脏疾病的机制和应用的全面审查。首先讨论肝脏疾病和常规治疗方法，该综述深入研究了脂质体的结构和组成。此外，它解决了脂质体靶向的不同机制，包括被动和主动策略。之后,该综述继续探讨脂质体纳米载体治疗肝硬化的治疗潜力，纤维化，病毒性肝炎,和肝细胞癌。通过讨论最近的进步和展望未来的前景，本综述重点介绍了脂质体纳米载体在提高肝脏疾病的有效性和安全性,从而改善患者预后和提高生活质量方面的作用.
